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SJG-136
go.drugbank.com/drugs/DB11965InvestigationalSJG-136 has been used in trials studying the treatment of Recurrent Fallopian Tube Cancer, Secondary Acute Myeloid Leukemia, de Novo Myelodysplastic Syndromes, Recurrent Ovarian Epithelial Cancer, and Secondary Myelodysplastic Syndromes,...
Categories: P-glycoprotein substratesLorvotuzumab mertansine
go.drugbank.com/drugs/DB12089InvestigationalLorvotuzumab mertansine has been used in trials studying the treatment of SCLC, Leukemia, Ovarian Cancer, Multiple Myeloma, and Merkel Cell Carcinoma, among others.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsSecoisolariciresinol
go.drugbank.com/drugs/DB12179InvestigationalSecoisolariciresinol has been used in trials studying the prevention of Breast Cancer.
Categories: P-glycoprotein inhibitorsEpofolate
go.drugbank.com/drugs/DB12266InvestigationalEpofolate (BMS-753493) is a folate conjugate of the epothilone analog BMS-748285 that was designed to selectively target folate receptor expressing cancer cells.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsRitanserin
go.drugbank.com/drugs/DB12693InvestigationalRitanserin has been used in trials studying the treatment of Cocaine-Related Disorders.
Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme InhibitorsTrofosfamide
go.drugbank.com/drugs/DB12902InvestigationalTrofosfamide has been used in trials studying the treatment of Ependymomas, Medulloblastomas, Sarcoma, Soft Tissue, Supratentorial PNETs, and Recurrent Brain Tumors.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesMethylprednisone
go.drugbank.com/drugs/DB12952ApprovedInvestigationalWithdrawnMethylprednisone has been used in trials studying the treatment of Leukemia, Rheumatoid Arthritis, Renal Transplantation, Kidney Transplantation, and Acute Lymphocytic Leukemia, among others.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesCloranolol
go.drugbank.com/drugs/DB13508ExperimentalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates9-Methylguanine
go.drugbank.com/drugs/DB02489ExperimentalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesBrefeldin A
go.drugbank.com/drugs/DB07348ExperimentalA metabolite from Penicillium brefeldianum that exhibits a wide range of antibiotic activity.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A Inhibitors