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Tuberculin purified protein derivative
go.drugbank.com/drugs/DB11601ApprovedTuberculin Purified Protein Derivative (PPD) is a sterile aqueous solution of a purified protein fraction for intradermal administration as an aid in the diagnosis of tuberculosis. … It is included in the World Health Organization's List of Essential Medicines.
Categories: Compounds used in a research, industrial, or household settingViltolarsen
go.drugbank.com/drugs/DB15005ApprovedInvestigationalis contingent on further verification in confirmatory trials. … [A218176] Viltolarsen was granted accelerated FDA approval on August 12, 2020, based on data showing an increase in dystrophin levels in skeletal muscle of patients treated with viltolarsen; this approval
Ammonia
go.drugbank.com/drugs/DB11118ApprovedInvestigationalIt is present in normally present in all tissues constituting a metabolic pool, where it is mostly taken up by glutamic acid and take part in transamination and other reactions, including the synthesis … of protein by the Krebs-Hanseleit cycle in the liver [L2033].
Mixtures: Physician EZ Use Joint Tunnel and Trigger Kit, Physician EZ Use Joint Tunnel and Trigger KitLanadelumab
go.drugbank.com/drugs/DB14597ApprovedInvestigational[A38676] Lanadelumab was approved for use in patients with hereditary angioedema by the FDA in August 2018,[L4537] followed by Health Canada in October 2018[L49226] and the EMA in November 2018. … [L4538] It is a fully human immunoglobulin, k-light-chain made in recombinant Chinese Hamster Ovary cells.
Categories: Drugs Used in Hereditary AngioedemaThimerosal
go.drugbank.com/drugs/DB11590ApprovedAlthough thimerosal is banned in several countries, it continues to be included as a preservative in some vaccines in the United States and many vaccines in the developing world [L1685]. … Thiomersal (INN), commonly known in the U.S. as thimerosal, is an organomercury compound. This compound is a well-established and widely used antiseptic and antifungal agent.
Categories: Compounds used in a research, industrial, or household settingVosoritide
go.drugbank.com/drugs/DB11928ApprovedInvestigational[L39229] It was approved for use under the brand name Voxzogo (BioMarin Pharmaceutical Inc.) in the EU in August 2021 and the US in November 2021,[L39245,L39241] becoming the first pharmacological intervention … [A242277] It results from a gain-of-function missense mutation in _FGFR3_ that results in a dramatic suppression of bone growth, both in volume and in length.
Nonoxynol-9
go.drugbank.com/drugs/DB06804ApprovedWithdrawnN-9 has been in use for more than 30 years as an over-the-counter (OTC) drug in creams, gels, foams and condom lubricants. … It is the most commonly used spermicidal contraceptive in the UK and the USA. In several European countries, spermicides are no longer on the market.
Categories: Compounds used in a research, industrial, or household settingDonislecel
go.drugbank.com/drugs/DB17961Approved[L47166,L47196] The approval of donislecel was based on the safety and effectiveness evaluated in 2 clinical trials with 30 type 1 diabetic patients. … [L47196] Donislecel was approved by the FDA on June 28, 2023, and is available under the brand name LANTIDRA from CellTrans Inc.[L47196]
Categories: Drugs Used in DiabetesIcodextrin
go.drugbank.com/drugs/DB00702ApprovedInvestigationalIcodextrin is an iso-osmotic peritoneal dialysis solution containing glucose polymers. … It is used primarily for ambulatory peritoneal dialysis (CAPD) of diabetic patients and automated peritoneal dialysis (APD) for patients with end-stage renal disease.
Categories: Compounds used in a research, industrial, or household settingZidovudine
go.drugbank.com/drugs/DB00495ApprovedInvestigationalA dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. … Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia. [PubChem]
Mixtures: LAMIVUDINA E ZIDOVUDINA MYLAN, LAMIVUDINA E ZIDOVUDINA MYLANCategories: Antivirals used in combination for the treatment of HIV infections