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Aceclofenac
go.drugbank.com/drugs/DB06736ApprovedAceclofenac belongs to BCS Class II as it possesses poor aqueous solubility [A19667]. … In 1991, aceclofenac was developed as an analog of a commonly prescribed NSAID, [DB00586], via chemical modification in effort to improve the gastrointestinal tolerability of the drug.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesProducts: ASEC 100 MG FILM TABLET, 20 ADET, BİOFENAC 100 MG FİLM KAPLI TABLET, 20 ADETIsoprenaline
go.drugbank.com/drugs/DB01064ApprovedInvestigational[L33204] Isoprenaline was granted FDA approval on 19 February 1948.[L33155] … [A15638,L33160] Isoprenaline research in the 1940s found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising the heart rate and cardiac output, without vasoconstriction
Products: ASTERAL SUBLINGUAL TABLET, 1000 ADET, ENAXİL 1 MG/5 ML ENJEKSİYONLUK ÇÖZELTİ, 5 ADETClonazepam
go.drugbank.com/drugs/DB01068ApprovedIllicitInvestigationalNow available as a generic medication, the agent continues to see exceptionally high use as millions of prescriptions are written for the medication internationally every year. … [FDA Label][L5572,F3763,F3787,F3796] The agent has also been indicated for treating panic disorder.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 InhibitorsSynonyms: 1,3-dihydro-7-nitro-5-(2-chlorophenyl)-2H-1,4.benzodiazepin-2-one, 5-(2-chlorophenyl)-7-nitro-1H-benzo[e][1,4]diazepin-2(3H)-oneFluticasone furoate
go.drugbank.com/drugs/DB08906ApprovedInvestigationalFluticasone furoate is a synthetic glucocorticoid available as an inhaler and nasal spray for various inflammatory indications[FDA Label][F4364]. Fluticasone furoate was first approved in 2007[L5965].
Mixtures: RELVAR ELLIPTA 100/25 MCG KULLANIMA HAZIR INHALASYON TOZU ,3 X 30, REVINTY ELLIPTA 100/25 MCG KULLANIMA HAZIR INHALASYON TOZU, 30 D0ZCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersLevamisole
go.drugbank.com/drugs/DB00848ApprovedInvestigationalVet approvedWithdrawn[A178117] It was manufactured by _Janssen_ and first used in 1969 as an agent to treat worm infestations[A178123] Levamisole was approved by the FDA in 1990 as an adjuvant treatment for colon cancer. … [L6232] Prior to this, levamisole was used as an antirheumatic therapy in the 1970s and 1980s for patients with rheumatoid arthritis.
Products: PARAKS 40 MG TABLET, 1000 ADET, PARAKS 40 MG/5 ML ŞURUP, 30 MLOmalizumab
go.drugbank.com/drugs/DB00043ApprovedInvestigational[A39518] Omalizumab was first approved in the US in 2003 [A263507] and in Europe in 2005.
Products: XOLAIR ® 150 MG, XOLAIR 150 MG ENJEKSIYONLUK COZELTI İÇİN TOZ İÇEREN FLAKON, 1 ADETAnagrelide
go.drugbank.com/drugs/DB00261ApprovedInvestigational[L14153] It is an oral imidazoquinazoline that was first approved for use in the US in 1997.[A214274] It appears to carry a better response rate than other thrombocythemia treatments (e.g.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsProducts: ANAGLYN 0,5 MG SERT KAPSÜL, 100 KAPSÜL, GRAFTA 0.5 MG SERT KAPSÜL, 100 ADETRibavirin
go.drugbank.com/drugs/DB00811ApprovedInvestigationalAddition of weight-based ribavirin to Technivie therapy increased sustained virologic response after 12 weeks of daily therapy (SVR12) from 90% to 97% in patients with HCV genotype 1a and 90.9% to 100% … The dual therapy was administered for 48 weeks in patients with genotype 1, 4, 5, and 6, and 24 weeks in patients with genotype 2 and 3 [A19626].
Mixtures: Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules)Products: VIRON 400 MG FİLM KAPLI TABLET, 56 ADET, VIRON 600 MG FİLM KAPLI TABLET, 56 ADETUdenafil
go.drugbank.com/drugs/DB06267ApprovedUdenafil is a new phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED). It has been approved in South Korea and will be marketed under the brand name Zydena.
Categories: Phosphodiesterase 5 Inhibitors, Cytochrome P-450 SubstratesProducts: ZYDENA 100 MG, ZYDENA 100 MG FILM TABLET, 2 ADETEconazole
go.drugbank.com/drugs/DB01127ApprovedA broad spectrum antimycotic with some action against Gram positive bacteria. It is used topically in dermatomycoses also orally and parenterally.
Categories: Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 CYP3A InhibitorsProducts: Pevaryl 10 mg/g Creme, Gyno-Pevaryl 10 mg/g Vaginalcreme