Search
Bunamidine
go.drugbank.com/drugs/DB11501ExperimentalVet approvedBunamidine is a veterinary anti-platyhelmintic agent used for taenia infestations.
Synonyms: N,N-Dibutyl-4-(hexyloxy)-1-naphthamidine, N,N-Dibutyl-4-hexyloxy-1-naphthamidinCefovecin
go.drugbank.com/drugs/DB11505ExperimentalVet approvedCefovecin is a cephalosporin antibiotic used for the treatment of skin infections in cats and dogs. … It is used for the treatment of skin infections caused by Pasturella multocida in cats, and Staphylococcus intermedius/S. canis in dogs.
Categories: Heterocyclic Compounds, 2-RingZolazepam
go.drugbank.com/drugs/DB11555ExperimentalVet approvedZolazepam is a pyrazolodiazepinone derivative used as an anaesthetic in veterinary medicine.
Categories: Heterocyclic Compounds, 2-RingAluminum chlorohydrate
go.drugbank.com/drugs/DB11573ApprovedAluminum chlorohydrate is a group of water-soluble aluminum complexes with the general formula AlnCl(3n-m)(OH)m. … It is also used as a coagulant in the water purification process.
Mixtures: KURSEPT %19 + %1 KREM (30 G), PERS-MANT %19 + %2 JEL (30 G)Products: 5 Day, A BilleGrazoprevir
go.drugbank.com/drugs/DB11575ApprovedGrazoprevir is an inhibitor of NS3/4A, a serine protease enzyme, encoded by HCV genotypes 1 and 4 [synthesis]. … in combination with [DB11574] for genotypes 1a, 1b, and 4 of Hepatitis C [A19593].
Mixtures: ZEPATIER® TABLETAS RECUBIERTASCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesAsunaprevir
go.drugbank.com/drugs/DB11586ApprovedWithdrawnAsunaprevir, also named BMS-650032, is a potent hepatitis C virus (HCV) NS3 protease inhibitor. … It has been shown to have a very high efficacy in dual-combination regimens with daclatasvir in patients chronically infected with HCV genotype 1b.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: SUNVEPRA® 100MG CÁPSULAS BLANDASDomiphen
go.drugbank.com/drugs/DB11594ApprovedDomiphen bromide is a quaternary ammonium compound that is predominantly employed as a topically administered antiseptic agent.
Synonyms: 1-dodecanaminium, n,n-dimethyl-n-(2-phenoxyethyl), Dodecyldimethyl(2-phenoxyethyl)ammoniumVelpatasvir
go.drugbank.com/drugs/DB11613ApprovedInvestigationalVelpatasvir acts as a defective substrate for NS5A (Non-Structural Protein 5A), a non-enzymatic viral protein that plays a key role in Hepatitis C Virus replication, assembly, and modulation of host immune … Velpatasvir is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV).
Mixtures: EPCLUSA®Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsArtenimol
go.drugbank.com/drugs/DB11638ApprovedInvestigationalArtenimol is an artemisinin derivative and antimalarial agent used in the treatment of uncomplicated Plasmodium falciparum infections [FDA Label]. It was first authorized for market by the European Medicines Agency in October 2011 in com...
Mixtures: D-ARTEPP, D-ARTEPP DISPERSIBLECategories: Cytochrome P-450 CYP2C19 Inhibitors, Cytochrome P-450 CYP2D6 InhibitorsVinflunine
go.drugbank.com/drugs/DB11641ApprovedInvestigationalWhile these patients have a median survival of approximately 4 months and a poor prognosis [L1396], there is currently no standard therapy in patients with advanced urothelial carcinoma [A32626]. … Like other vinca agents, vinflunine is an anti-mitotic agent that induces a cell cycle arrest at the G2/M phase and promotes cell death via apoptosis [L1396].
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: 20',20'-difluoro-3',4'-dihydrovinorelbine, 4'-deoxy-20',20'-difluoro-5'-norvincaleukoblastine