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Displaying results 8551 - 8560 of 10000 in total
  1. Drug

    SR-9011

    go.drugbank.com/drugs/DB14014
    Experimental

    SR-9011 is a REV-ERB agonist. … SR-9011 has been demonstrated that it is specifically lethal to cancer cells and oncogene-induced senescent cells, including melanocytic naevi, and has no effect on the viability of normal cells or tissues

  2. Drug

    SS1(dsFv)-PE38

    go.drugbank.com/drugs/DB17579
    Investigational

    SS1(dsFv)-PE38 is a recombinant anti-mesothelin immunotoxin. … SS1(dsFv)-PE38 is under investigation in clinical trial NCT01051934 (A Phase I Trial of SS1 (Dsfv) PE38 With Paclitaxel, Carboplatin, and Bevacizumab in Subjects With Unresectable Non-small Cell Lung Adenocarcinoma

  3. Drug

    Linopristin

    go.drugbank.com/drugs/DB19296
    Experimental

    Linopristin is an antibiotic of the streptogramin B class. It is one part of the combination product NXL 103, along with [Virginiamycin M1].

  4. Drug

    (R)-warfarin

    go.drugbank.com/drugs/DB08496
    Experimental

    S-warfarin is 2-5 times more potent than the R-isomer in producing an anticoagulant response.[A1038] … Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways.

  5. Drug

    Prostaglandin D2

    go.drugbank.com/drugs/DB02056
    Experimental

    It is released upon activation of mast cells and is also synthesized by alveolar macrophages.

  6. Drug

    5-deoxyflavanone

    go.drugbank.com/drugs/DB03601
    Experimental

    5-deoxyflavanone is a solid. This compound belongs to the flavanones. … These are compounds containing a flavan-3-one moiety, whose structure is characterized by a 2-phenyl-3,4-dihydro-2H-1-benzopyran bearing a ketone at the carbon C3.

  7. Drug

    Dibromothymoquinone

    go.drugbank.com/drugs/DB04646
    Experimental

    At low concentrations, this compound inhibits reduction of conventional hydrophilic electron acceptors, probably acting as a plastoquinone antagonist. … At higher concentrations, it acts as an electron acceptor, intercepting electrons either before or at the site of its inhibitory activity. [PubChem]

  8. Drug

    Irampanel

    go.drugbank.com/drugs/DB21123
    Investigational

    Irampanel is a small molecule drug. … Irampanel is under investigation in clinical trial NCT02222961 (Single Increasing Dose Followed by Maintenance Dose Tolerance Study of BIIR 561 CL in Healthy Male Volunteers).

  9. Drug

    Salacetamide

    go.drugbank.com/drugs/DB20217
    Investigational

    Salacetamide is a small molecule drug. … Salacetamide is under investigation in clinical trial NCT00220285 (Study for Evaluation of Efficacy and Safety of SH L 749 to Indolent B-cell Non-Hodgkin's Lymphoma).

  10. Drug

    Aftobetin

    go.drugbank.com/drugs/DB20425
    Investigational

    Aftobetin is a small molecule drug. … Aftobetin is under investigation in clinical trial NCT02928211 (Aftobetin-HCl and Fluorescence Detection Measured by Sapphire II to Determine the Number and Timing of Administrations).