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Displaying results 8581 - 8590 of 10000 in total
  1. Drug

    AV-COVID-19

    go.drugbank.com/drugs/DB15802
    Investigational

    As of July 2020, the company is pursuing an adaptive Phase IB-II Randomized Clinical Trial (NCT04386252) to test the vaccine. … The monocytes are then differentiated in vitro into dendritic cells with IL-4 and GM-CSF, incubated with SARS-CoV-2 antigens prior to administration.

  2. Drug

    Mephenytoin

    go.drugbank.com/drugs/DB00532
    ApprovedWithdrawn

    Mephenytoin and oxazolidinedione derivatives are associated with higher incidences of blood dyscrasias compared to other anticonvulsants. … These are heterocyclic aromatic compounds containing an imiazolidinedione moiety substituted by a phenyl group. Mephenytoin is known to target sodium channel protein type 5 subunit alpha.

  3. Drug

    HPA-23

    go.drugbank.com/drugs/DB17739
    Experimental

    HPA-23 is an investigational antiviral compound.[A259142]

  4. Drug

    3,5-diiodothyropropionic acid

    go.drugbank.com/drugs/DB12629
    Investigational

    DITPA has been investigated in Congestive Heart Failure.

  5. Drug

    TO-901317

    go.drugbank.com/drugs/DB07080
    Experimental

    TO-901317 is an LXRalpha and LXRbeta agonist.

  6. Drug

    CoVac-1

    go.drugbank.com/drugs/DB16429
    Investigational

    It is being investigated in the clinical trial NCT04546841 (Safety and Immunogenicity Trial of Multi-peptide Vaccination to Prevent COVID-19 Infection in Adults (pVAC))[L30428] and aims to induce broad … Sponsored by the University Hospital Tuebingen in Germany, CoVac-1 is a multi-peptide COVID-19 vaccine candidate created from HLA class I and HLA-DR T-cell epitopes of the S-protein[A226588].

    Categories: Complex Mixtures
  7. Drug

    Alfaxalone

    go.drugbank.com/drugs/DB11371
    ExperimentalVet approved

    It is used in veterinary practice under the trade name Alfaxan, and is licensed for use in both dogs and cats.

  8. Drug

    QAV-680

    go.drugbank.com/drugs/DB11658
    Investigational

    QAV680 has been used in trials studying the treatment of Asthma, Allergic Rhinitis, and Seasonal Allergic Rhinitis.

  9. Drug

    Landogrozumab

    go.drugbank.com/drugs/DB11862
    Investigational

    Landogrozumab has been used in trials studying the treatment of Advanced Cancer, Muscular Atrophy, and Pancreatic Cancer.

  10. Drug

    Rivoceranib

    go.drugbank.com/drugs/DB14765
    Investigational

    Rivoceranib is under investigation in clinical trial NCT02726854 (Apatinib as Second-line Treatment of Advanced Pancreatic Cancer).