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Timolol
go.drugbank.com/drugs/DB00373ApprovedInvestigational[L6724] It is also used in tablet form as a drug to treat hypertension.[L6727] Timolol was first approved by the FDA in 1978. … Timolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes.
Mixtures: AZARGA 10 MG/ML + 5 MG/ML, BRİTİL-T 10 MG/ML + 5 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 1 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesEthosuximide
go.drugbank.com/drugs/DB00593ApprovedInvestigationalAn anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: PETIMID 250 MG KAPSUL, 50 ADET, Ethosuximid neuraxpharm 50 mg/ml Lösung zum EinnehmenHepatitis A Vaccine
go.drugbank.com/drugs/DB10989ApprovedInvestigationalHepatitis A viral infection can lead to significant morbidity and mortality, with signs and symptoms that include anorexia, nausea, vomiting, and liver failure. … against the disease caused by infection with this virus.
Mixtures: TWINRIX ERİŞKİN IM 1 ML SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, TWINRIX PEDİATRİK IM 0.5 ML SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖRProducts: AVAXIM 160 U 0.5 ML IM ENJEKSİYON İÇİN SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET, VAQTA 50 E/1 ml InjektionssuspensionLorlatinib
go.drugbank.com/drugs/DB12130ApprovedInvestigationalIt was subsequently approved by the EMA in 2019 for the treatment of select patients with previously treated advanced ALK-positive non-small cell lung cancer, followed by an expanded approval in 2022 to … Lorlatinib is a third-generation ALK tyrosine kinase inhibitor (TKI) for patients with ALK-positive metastatic non-small cell lung cancer[L39905] which was first approved by the US FDA in November of 2018
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersProducts: LORBRENA® 100 MG, LORVIQUA (TABLETS 100 MG)Clomifene
go.drugbank.com/drugs/DB00882ApprovedInvestigationalA triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.
Products: KLOMEN 50 MG TABLET, 10 ADET, KLOMEN 50 MG, 30 ADETUmeclidinium
go.drugbank.com/drugs/DB09076ApprovedInvestigational[A7719] By blocking the M3 muscarinic receptor, umeclidinium inhibits the binding of acetylcholine and thereby opens up the airways by preventing bronchoconstriction. … [A7715] Maintenance of the airway is controlled by the parasympathetic nervous system, particularly by the abundance of the muscarinic subtype 3 (M3) in the airway smooth muscle.
Mixtures: TRELEGY ELLİPTA 100 MCG + 62,5 MCG +25 MCG KULLANIMA HAZIR İNHALASYON TOZU, 30 DOZ, TRELEGY ELLIPTA INHALATION POWDER 100 MCG/62.5 MCG/25 MCGCategories: Agents to Treat Airway Disease, Cytochrome P-450 SubstratesRamipril
go.drugbank.com/drugs/DB00178ApprovedInvestigationalRamipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. … Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII).
Mixtures: Trinomia 100 mg/20 mg/10 mg Hartkapseln, Trinomia 100 mg/40 mg/10 mg HartkapselnProducts: ANGIRAM 10 (Ramipril Tablets 10 mg), Hypren 10 mg - TablettenBortezomib
go.drugbank.com/drugs/DB00188ApprovedInvestigationalapoptosis of cancer cells, is thought to be the main mechanism of action of bortezomib. … Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma and mantle cell lymphoma.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsProducts: BOTEMIB 1.0 MG, BORTEZOMIB POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE 3.5MG/VIAL 10 MLAbacavir
go.drugbank.com/drugs/DB01048ApprovedInvestigationalIn vivo, abacavir sulfate dissociates to its free base, abacavir. … Abacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS.
Mixtures: TRIUMEQ® 50 MG / 600 MG / 300 MG, TRIUMEQ 50 MG/600 MG/300 MG FILM KAPLI TABLET,90 FILM KAPLI TABLETProducts: ABAMAT PED® 60 MG, ZIAGEN 300 MG FİLM KAPLI TABLET, 30 ADETMethyl aminolevulinate
go.drugbank.com/drugs/DB00992ApprovedInvestigationalMethyl aminolevulinate is a prodrug that is metabolised to Protoporphyrin IX (a photosensitizer) used in photodynamic therapy.
Synonyms: methyl 5-aminolevulinate, 5-aminolevulinic acid methyl esterProducts: Luxerm 160 mg/g Creme, Metvix 160 mg/g Creme