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Alendronic acid
go.drugbank.com/drugs/DB00630ApprovedInvestigationalAlendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111].
Mixtures: OSSOFORTIN A 70 MG+1200 MG/800 IU TEDAVİ PAKETİ, 4+24 ADET, BONMEGA 70 MG/2800 IU+1000 MG TEDAVI PAKETI, 4+24 ADETProducts: ALENDRONATO 10 MG, LENDO 10 MG TABLET, 28 ADETUmeclidinium
go.drugbank.com/drugs/DB09076ApprovedInvestigational[A7719] By blocking the M3 muscarinic receptor, umeclidinium inhibits the binding of acetylcholine and thereby opens up the airways by preventing bronchoconstriction. … [A7715] Maintenance of the airway is controlled by the parasympathetic nervous system, particularly by the abundance of the muscarinic subtype 3 (M3) in the airway smooth muscle.
Mixtures: TRELEGY ELLIPTA INHALATION POWDER 100 MCG/62.5 MCG/25 MCG, TRELEGY ELLİPTA 100 MCG + 62,5 MCG + 25 MCG KULLANIMA HAZIR İNHALASYON TOZUCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesPhentermine
go.drugbank.com/drugs/DB00191ApprovedIllicitInvestigationalPhentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity combination drug. … [A174376, T403] Later on, phentermine was approved alone and in combination with topiramate in 2012 as a new alternative that required lower doses of phentermine to obtain the desired effect.[A174373]
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Cytochrome P-450 SubstratesProducts: PANBESY CAPSULE 15 MG, DUROMINE CAPSULE 15 mgPerazine
go.drugbank.com/drugs/DB12710ApprovedWithdrawnPerazine has been used in trials studying the treatment of Dementia, Depression, Schizophrenia, Anxiety Disorders, and Psychosomatic Disorders, among others.
Products: PERAZIN-NEURAX 100 MG, PERAZIN-NEURAX 25 MGNicergoline
go.drugbank.com/drugs/DB00699ApprovedAn ergot derivative that has been used as a cerebral vasodilator and in peripheral vascular disease. It has been suggested to ameliorate cognitive deficits in cerebrovascular disease.
Synonyms: 10-methoxy-1,6-dimethylergoline-8β-methanol 5-bromonicotinate, (8β)-10-methoxy-1,6-dimethylergoline-8-methanol 5-bromo-3-pyridinecarboxylate (ester)Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesFlucytosine
go.drugbank.com/drugs/DB01099ApprovedInvestigationalA fluorinated cytosine analog that is used as an antifungal agent.
Products: FLUSYNERG® 10 MG/ML SOLUCIÓN INYECTABLE, Ancotil 2,5 g/250 ml -InfusionsflaschenSilibinin
go.drugbank.com/drugs/DB09298InvestigationalSilibinin is presented as a mixture of two diastereomers, silybin A and silybin B, which are found in an approximately equimolar ratio. … Silibinin is the major active constituent of silymarin, a standardized extract of the milk thistle seeds, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silicristin, silidianin
Categories: Compounds used in a research, industrial, or household settingSynonyms: Silibinin A, Silybin ACanrenoic acid
go.drugbank.com/drugs/DB09015ApprovedInvestigationalWithdrawnLike spironolactone, it is a prodrug, which is metabolized to canrenone in the body.
Products: Aldactone 200 mg/ 10 ml Injektionslösung, POTASSIO CANRENOATO EGTolcapone
go.drugbank.com/drugs/DB00323ApprovedInvestigationalWithdrawnIt is a yellow, odorless, non-hygroscopic, crystalline compound. Tolcapone is associated with a risk of hepatotoxicity. … Tolcapone is a drug that inhibits the enzyme catechol-O-methyl transferase (COMT). It is used in the treatment of Parkinson's disease as an adjunct to levodopa/carbidopa medication.
Categories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme InhibitorsProducts: TASMAR ROCHE TABLETA LACADA DE 100 MG, TASMAR ROCHE TABLETAS LACADAS DE 200 MGClorazepic acid
go.drugbank.com/drugs/DB00628ApprovedIllicitSimilar to other benzodiazepines, the active metabolite of clorazepate enhances the binding of gamma-aminobutyric acid (GABA) to the GABA type A (GABA-A) receptor, which promotes channel opening and neuronal … Clorazepic acid (clorazepate) is a water-soluble benzodiazepine with muscle-relaxant and anticonvulsant actions effective in the treatment of anxiety.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: TRANXILENE 10 MG KAPSUL, 50 ADET, ANKSEN 10 MG KAPSÜL, 30 KAPSÜL