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Gadopentetic acid
go.drugbank.com/drugs/DB00789ApprovedInvestigationalA complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see pentetic acid), that is given to enhance the image in cranial and spinal MRIs.
Categories: Compounds used in a research, industrial, or household settingProducts: Magnevist 2 mmol/l - Injektionslösung, MAGNEVIST FLAKON, 5 MLTripelennamine
go.drugbank.com/drugs/DB00792ApprovedVet approvedTripelennamine is administered by various routes, including topically. … A histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. It is used to treat asthma; HAY fever; urticaria; and rhinitis; and also in veterinary applications.
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP2D6 InhibitorsProducts: Vaginex W Tripelennamine Crm 2%, Vagin-XHaloprogin
go.drugbank.com/drugs/DB00793ApprovedWithdrawnHaloprogin is used as a topical ointment or cream in the treatment of Tinea infections. … Haloprogin is a halogenated phenolic ether administered topically for dermotaphytic infections.
Primidone
go.drugbank.com/drugs/DB00794ApprovedVet approved[L11112] Primidone was developed by J Yule Bogue and H C Carrington in 1949.[A189522] Primidone was granted FDA Approval on 8 March 1954.[L11112] … Primidone is an anticonvulsant used to treat essential tremor as well as grand mal, psychomotor, and focal epileptic seizures.
Synonyms: 5-Phenyl-5-ethyl-Hexahydropyrimidine-4,6-dione, 2-deoxyphenobarbitalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InducersHalazepam
go.drugbank.com/drugs/DB00801ApprovedIllicitWithdrawnHalazepam is a _benzodiazepine_ derivative drug exerting anxiolytic, anticonvulsant, sedative, a muscle relaxing effects. … [A1212] This drug is no longer marketed in the United States, and was withdrawn by _Schering_, its manufacturer, in 2009.[L6226, L6229]
Categories: Heterocyclic Compounds, 2-RingMinaprine
go.drugbank.com/drugs/DB00805ApprovedMinaprine is a psychotropic drug which has proved to be effective in the treatment of various depressive states. Like most antidepressants minaprine antagonizes behavioral despair. … Minaprine is an amino-phenylpyridazine antidepressant reported to be relatively free of cardiotoxicity, drowsiness, and weight gain.
Synonyms: 4-(2-((4-Methyl-6-phenyl-3-pyridazinyl)amino)ethyl)morpholine, N-(4-Methyl-6-phenyl-3-pyridazinyl)-4-morpholineethanamineCategories: Cytochrome P-450 Substrates, Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesIndapamide
go.drugbank.com/drugs/DB00808ApprovedInvestigational[A204134,A204161] Indapamide is characterized by both a methylindoline and a sulfamoyl chlorobenzamide functional group, with the former being largely responsible for the molecule’s lipid solubility … [A204155] Thiazide-like diuretics such as indapamide are a valuable tool for the treatment of hypertension and continue to grow in popularity, falling behind only ACE inhibitors in terms of prescription
Synonyms: BR1015-2Mixtures: PERDUO 4/1.5 MG SR FILM KAPLI TABLET, 30 ADET, PERDUO 4/1.5 MG SR FILM KAPLI TABLET, 90 ADETRibavirin
go.drugbank.com/drugs/DB00811ApprovedInvestigationalThe dual therapy was administered for 48 weeks in patients with genotype 1, 4, 5, and 6, and 24 weeks in patients with genotype 2 and 3 [A19626]. … When used to treat Hepatitis C virus (HCV) infections, it is always used as a part of combination therapies as ribavirin monotherapy is not efficacious in the treatment of chronic hepatitis C infection
Synonyms: 1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide, 1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamideCategories: Treatments for Hepatitis CMeloxicam
go.drugbank.com/drugs/DB00814ApprovedInvestigationalVet approvedIt is a preferential COX-2 inhibitor, purportedly reducing the risk of adverse gastrointestinal tract effects, however, this is a topic of controversy.[A190198,A190201] … [A190189] With a longer half-life than most other NSAIDS, it is a favorable option for those who require once-daily dosing. Meloxicam is available in oral, transdermal, and intravenous formulations.
Mixtures: NURO-B, NURO-BCategories: COX-2 Inhibitors, Cytochrome P-450 SubstratesSodium lauryl sulfate
go.drugbank.com/drugs/DB00815ApprovedSLS lowers surface tension of aqueous solutions and is used as fat emulsifier, wetting agent, and detergent in cosmetics, pharmaceuticals and toothpastes. … It is also used in creams and pastes to properly disperse the ingredients and as research tool in protein biochemistry. SLS also has some microbicidal activity.
Categories: Compounds used in a research, industrial, or household setting