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Treprostinil
go.drugbank.com/drugs/DB00374ApprovedInvestigational[L41860] It is available in the following routes of administration: subcutaneous, intravenous, inhaled and oral. The first generic form of treprostinil became available in 2019.[A248775] … However, the use of epoprostenol is limited due to its short half-life (3-5 min) and instability at room temperature.
Categories: Prostaglandins I, Cytochrome P-450 SubstratesProducts: REMODULIN ® INYECCIÓN 1 MG/ML, TIMERAXONE ® 5MG/MLTacrine
go.drugbank.com/drugs/DB00382ApprovedWithdrawnA centerally active cholinesterase inhibitor that has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous
Synonyms: 1,2,3,4-tetrahydro-9-acridinamine, 1,2,3,4-tetrahydro-9-aminoacridineCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesOxyphencyclimine
go.drugbank.com/drugs/DB00383ApprovedOxyphencyclimine is an anticholinergic drug (trade name Daricon) used in treating peptic ulcers.
Categories: Heterocyclic Compounds, 1-RingProducts: ออกซี่เฟน 5, ยาเม็ด อ๊อกซีเฟนไซคลีมีน (5 มก.)Valrubicin
go.drugbank.com/drugs/DB00385ApprovedValrubicin (N-trifluoroacetyladriamycin-14-valerate) is a chemotherapy drug commonly marketed under the trade name VALSTAR. … It is a semisynthetic analog of the [doxorubicin], which is an anthracycline drug. Used in the treatment of the bladder cancer, valrubicin is administered by direct infusion into the bladder.
Synonyms: 2-oxo-2-[(2S,4S)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-4-({2,3,6-trideoxy-3-[(trifluoroacetyl)amino]hexopyranosyl}oxy)-1,2,3,4,6,11-hexahydrotetracen-2-yl]ethyl pentanoate, (8S, 10S)-8-glycoloyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-10-[[2,3,6-trideoxy-3-(2,2,2-trifluoroacetamido)-α-L-lyxo-hexopyranosyl]oxy]-5,12-naphthacenedione 8²-valerateCarbimazole
go.drugbank.com/drugs/DB00389ApprovedCarbimazole is metabolized to methimazole, which is responsible for the antithyroid activity.
Synonyms: Ethyl 3-methyl-2-thioimidazoline-1-carboxylateCategories: Heterocyclic Compounds, 1-RingCarisoprodol
go.drugbank.com/drugs/DB00395ApprovedIn January 2012, this drug was classified as a Schedule IV substance under the controlled substances act in several US states due to alarming rates of abuse [A176062, A176077] despite having a low potential … for abuse in addition to a low risk of dependence [L5074].
Synonyms: N-isopropy-2-methyl-2-propyl-1,3-propanediol dicarbamate, (RS)-2-{[(aminocarbonyl)oxy]methyl}-2-methylpentyl isopropylcarbamateCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesCeruletide
go.drugbank.com/drugs/DB00403ApprovedIt exerts stimulatory effects on the gastric, biliary, and pancreatic secretion, as well as on certain smooth muscles. … Caerulein is a specific decapeptide similar in action and composition to the natural gastrointestinal peptide hormone cholecystokinin.
Gentian violet cation
go.drugbank.com/drugs/DB00406ApprovedA dye that is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties.
Synonyms: Crystal violet(1+), Gentian violet(1+)Mixtures: Kerr 100 Triple Dye Dispos-ACarbamoylcholine
go.drugbank.com/drugs/DB00411ApprovedCarbamoylcholine, also known as carbachol, is a muscarinic agonist discovered in 1932. … [A226315] Carbamoylcholine was initially used as a treatment for migraines,[A226365] induction of diuresis,[A226370] and other parasympathetic effects.
Categories: Compounds used in a research, industrial, or household settingProducts: Carbachol Injection Liq Sc 0.25mg/ml, Isopto Carbachol 3%Metocurine iodide
go.drugbank.com/drugs/DB00416ApprovedWithdrawnMetocurine Iodide is no longer available on the US market. … Metocurine iodide is a benzylisoquinolinium competitive nondepolarizing neuromuscular blocking agent.
Categories: Heterocyclic Compounds, 2-Ring