Oxyphencyclimine is a drug used to treat smooth muscle spasticity. Oxyphencyclimine is an anticholinergic drug (trade name Daricon) used in treating peptic ulcers.
- Mechanism
- Curator reviewed
Oxyphencyclimine binds the muscarinic acetylcholine receptor. It may block all three types of muscarinic receptors including M-1 receptors in the CNS and ganglia, M-2 receptors in the heart (vagus) and M-3 receptors at the parasympathetic NEJ system. The muscarinic acetylcholine receptors mediate various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Oxphencyclimine inhibits vagally mediated reflexes by antagonizing the action of acetylcholine. This in turn reduces the secretion of gastric acids in the stomach.
- Primary indication
- For the treatment of peptic ulcer disease and the relief of smooth muscle spasms in gastrointestinal disorders.Curator reviewed · 1 structured indication
- Formula / weight
- C20H28N2O3 · 344.4479 g/mol (avg)
Resolves to
DUDKAZCAISNGQN-UHFFFAOYSA-NSMILESCN1CCCN=C1COC(=O)C(O)(C1CCCCC1)C1=CC=CC=C1What you can answer from here — as of September 13, 2026
Which drugs share a target with Oxyphencyclimine, and which of those have an active Phase 3 trial?
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