Carbimazole

DB00389ApprovedSmall molecule

Carbimazole is a drug used for the reduction of thyroid function. An imidazole antithyroid agent.

Mechanism: Carbimazole is an aitithyroid agent that decreases the uptake and concentration of inorganic iodine by thyroid, it also reduces the formation of di-iodotyrosine and thyroxine. Once converted to its active form of methimazole, it prevents the thyroid peroxidase enzyme from coupling and iodinating the tyrosine residues on thyroglobulin, hence reducing the production of the thyroid hormones T3 and T4.
Curator reviewed
Primary indication: For the treatment of hyperthyroidism and thyrotoxicosis.Curator reviewed · 1 structured indication
Formula / weight: C₇H₁₀N₂O₂S · 186.232 g/mol (avg)
Also known as: Athyromazole · Carbethoxymethimazole · Carbinazole
Code names: CG 1

Resolves to

Compound

UNII8KQ660G60GCAS22232-54-8ChEMBLCHEMBL508102ChEBI617099PubChem31072KEGGD07616

Clinical / RWD

RxNorm2020ATCH03BB01PharmGKBPA164742970

Structure

InChIKeyCFOYWRHIYXMDOT-UHFFFAOYSA-NSMILESCCOC(=O)N1C=CN(C)C1=S

Targets

P07202TPO

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

454Drug interactionsStructured to mechanism, not free text

5Clinical trialsPhase, status and sponsor resolved per trial

1Structured indicationCondition, population, route and combination as fields, not prose

5ContraindicationsEach with its own population and attribute set

25Marketed productsAcross 4 countries and 9 labellers

1ATC codeIncluding every combination product, plus 8 drug categories

16+ReferencesStructured and connected to the statements they support

Which drugs share a target with Carbimazole, and which of those have an active Phase 3 trial?

Answer this in Biopharma OS Sign in to your account

Create a free account or log in to explore the full data card.

Log In Paid Account Log In