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Opelconazole
go.drugbank.com/drugs/DB18251InvestigationalCategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 CYP3A InducersCC-90001
go.drugbank.com/drugs/DB18445InvestigationalCategories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsAPPD
go.drugbank.com/drugs/DB18603ExperimentalCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesP-42 peptide
go.drugbank.com/drugs/DB18610ExperimentalP-42 peptide is a synthetic 23 amino acid peptide AASSGVSTPGSAGHDIITEQPRS derived from the Huntingtin protein
Enavogliflozin
go.drugbank.com/drugs/DB18970InvestigationalEnavogliflozin is under investigation in clinical trial NCT06399835 (Enavogliflozin vs. Pioglitazone on Glucose and Atherosclerosis).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesAminoflavone
go.drugbank.com/drugs/DB19077InvestigationalAminoflavone is under investigation in clinical trial NCT01015521 (Efficacy Study of Aminoflavone Prodrug to Treat Breast Cancer).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesArketamine
go.drugbank.com/drugs/DB19150InvestigationalArketamine is under investigation in clinical trial NCT05414422 (A Randomized, Placebo-controlled, Double-blind Study to Assess Safety and Efficacy of PCN-101 in TRD).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesSubstance P
go.drugbank.com/drugs/DB19198InvestigationalSubstance P is under investigation in clinical trial NCT03738878 (Mechanism(s) Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 1).
Synonyms: Substance P, Neurokinin pCategories: Substance P, antagonists & inhibitorsImnopitant
go.drugbank.com/drugs/DB21456ExperimentalThe usage of the INN stem '-pitant' in the name indicates that Imnopitant is a neurokinin NK1 (substance P) receptor antagonist. Imnopitant has a monoisotopic molecular weight of 550.22 Da.
Zastaprazan
go.drugbank.com/drugs/DB21524InvestigationalZastaprazan is a small molecule drug. The usage of the INN stem '-prazan' in the name indicates that Zastaprazan is a proton pump inhibitor, not dependent on acid activation. Zastaprazan is under investigation in clinical trial NCT058148...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates