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Phenoxymethylpenicillin
go.drugbank.com/drugs/DB00417ApprovedInvestigationalVet approvedPhenoxymethylpenicillin is a narrow spectrum antibiotic also commonly referred to as Penicillin V or Penicillin VK.[A178609] It is a phenoxymethyl analog of Penicillin G, or [benzylpenicillin]. … Phenoxymethylpenicillin has also be used in some cases as prophylaxis against susceptible organisms.
Categories: Penicillin G, Heterocyclic Compounds, 1-RingSynonyms: (2S,5R,6R)-3,3-DIMETHYL-7-OXO-6-(2-PHENOXYACETAMIDO)-4-THIA-1- AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ACID, (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acidMiglustat
go.drugbank.com/drugs/DB00419ApprovedInvestigationalMiglustat is now the first and only approved therapy for patients with Niemann-Pick disease type C (NP-C). … Miglustat, commonly marketed under the trade name Zavesca, is a drug used to treat Gaucher disease.
Categories: Heterocyclic Compounds, 1-RingSynonyms: N-(n-Butyl)deoxynojirimycin, N-butyl-1-deoxynojirimycinPromazine
go.drugbank.com/drugs/DB00420ApprovedVet approvedWithdrawnA phenothiazine with actions similar to chlorpromazine but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic. … It is currently not approved for use in the United States.
Categories: Cytochrome P-450 Substrates, Adrenergic alpha-1 Receptor AntagonistsSynonyms: N,N-dimethyl-3-(10H-phenothiazin-10-yl)-propan-1-amine, N-(3-Dimethylaminopropyl)phenothiazineSpironolactone
go.drugbank.com/drugs/DB00421ApprovedInvestigationalSpironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. … [A11837, A178246] It is indicated to treat several conditions, including heart failure, edema, hyperaldosteronism, and hypertension.
Mixtures: Benzoyl Peroxide 5% / Clindamycin 1% / Niacinamide 2% / Spironolactone 2%, Dapsone 6% / Niacinamide 2% / Spironolactone 5%Categories: P-glycoprotein inducers, Cytochrome P-450 CYP2C8 InhibitorsZolpidem
go.drugbank.com/drugs/DB00425ApprovedInvestigationalZolpidem, also known as _Ambien_, is a hypnotic drug that was initially approved by the FDA in 1992 [FDA label]. Zolpidem improves sleep in patients with insomnia. … Research also shows that zolpidem is rapid and effective in restoring brain function for patients in a vegetative state following brain injury.
Mixtures: Gabazolpidem-5, Sentrazolpidem PM-5Categories: GABA-A Receptor Agonists, Cytochrome P-450 SubstratesStreptozocin
go.drugbank.com/drugs/DB00428ApprovedInvestigationalAn antibiotic that is produced by Stretomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
Categories: P-glycoprotein inducers, Cytochrome P-450 CYP1A2 InducersSynonyms: 1-METHYL-1-NITROSO-3-((2R,3R,4S,5R)-3,4,5,6-TETRAHYDROXY-1-OXOHEXAN-2-YL)UREA, 2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranoseNitric Oxide
go.drugbank.com/drugs/DB00435ApprovedInvestigationalThe nitric oxide molecule is a free radical, which is relevant to understanding its high reactivity. … Nitric oxide or Nitrogen monoxide is a chemical compound with chemical formula NO.
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP3A InhibitorsProducts: NOW st, INOFLO® LINDEBendroflumethiazide
go.drugbank.com/drugs/DB00436ApprovedInvestigationalA thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders.
Mixtures: Corzide Tab W Nadolol 80mg, Corzide Tab W Nadolol 40mgCategories: Heterocyclic Compounds, 2-RingAllopurinol
go.drugbank.com/drugs/DB00437ApprovedInvestigationalAllopurinol is a xanthine oxidase enzyme inhibitor that is considered to be one of the most effective drugs used to decrease urate levels and is frequently used in the treatment of chronic gout [A36705 … Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints [A175942].
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Heterocyclic Compounds, 2-RingSynonyms: 1H-Pyrazolo(3,4-d)pyrimidin-4-ol, 4-Hydroxypyrazolo(3,4-d)pyrimidineLevothyroxine
go.drugbank.com/drugs/DB00451ApprovedInvestigationalWhile T<sub>4</sub> is the major product secreted by the thyroid gland, T<sub>3</sub> exerts the majority of the physiological effects of the thyroid hormones; T<sub>4</sub> and T<sub>3</sub> have a relative … potency of ~1:4 (T4:T3).
Mixtures: L THYROX JOD HEXAL 50/150, L THYROX JOD HEXAL 50/150Categories: P-glycoprotein inducers, Cytochrome P-450 CYP2C8 Inhibitors