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Pipotiazine
go.drugbank.com/drugs/DB01621ApprovedInvestigationalWithdrawnAmong the different phenothiazine derivatives, it appears to be less sedating and to have a weak propensity for causing hypotension or potentiating the effects of CNS depressants and anesthetics. … It is used for the maintenance treatment of chronic non-agitated schizophrenic patients. Symptoms of overdose include severe extrapyramidal manifestations, hypotension, lethargy and sedation.
Products: PIPOTIAZINA 25MG/MLCinnarizine
go.drugbank.com/drugs/DB00568ApprovedInvestigationalFirst synthesized by Janssen Pharmaceuticals in 1955, cinnarizine is an anti-histaminic drug mainly used for the control of vestibular disorders and motion sickness. … Cinnarizine is a specific calcium channel blocker that primarily works on the central vestibular system to interfere with the signal transmission between vestibular apparatus of the inner ear and the vomiting
Categories: Calcium-Regulating Hormones and AgentsProducts: PRINAZIN TABLET 25MG, STUGERON 25MG TABLETVaricella zoster vaccine (recombinant)
go.drugbank.com/drugs/DB13924ApprovedInvestigationalRecombinant zoster vaccine, manufactured as the product Shingrix by GlaxoSmithKline, is an adjuvanted non-live recombinant vaccine indicated for prevention of shingles. … This is a significant improvement over its predecessor, Zostavax, which reduces the risk of shingles by only 51% and the risk of post-herpetic neuralgia by 67% [A31349].
Products: SHINGRIX POWDER AND SUSPENSION FOR SUSPENSION FOR INJECTION 50MCG/0.5MLCandesartan cilexetil
go.drugbank.com/drugs/DB00796ApprovedInvestigationalCandesartan lowers blood pressure by antagonizing the renin-angiotensin-aldosterone system (RAAS); it competes with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and prevents … Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension.
Mixtures: CAMLOSTAR 16MG/10MG, CAMLOSTAR 16MG/10MGCategories: Angiotensin II Antagonists and Diuretics, Agents Acting on the Renin-Angiotensin SystemInsulin aspart
go.drugbank.com/drugs/DB01306ApprovedInvestigationalInsulin is an important treatment in the management of Type 1 Diabetes (T1D) which is caused by an autoimmune reaction that destroys the beta cells of the pancreas, resulting in the body not being able … Insulin aspart is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.
Categories: Alimentary Tract and Metabolism, Amino Acids, Peptides, and ProteinsProducts: Fiasp® 100 units/ml, 10ml Vial, .Insulin Aspart Protamine and Insulin AspartTibolone
go.drugbank.com/drugs/DB09070ApprovedInvestigationalTibolone (Livial, Org OD 14), produced by Organon (West Orange, NJ), is a synthetic steroid that possesses estrogenic, androgenic and progestogenic properties. … Tibolone is approved in 90 countries to manage menopausal symptoms and in 45 countries to prevent the development of osteoporosis [L1876].
Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital SystemSynonyms: 17-hydroxy-7alpha-methyl-19-nor-17alpha-pregn-5(10)-en-20-yn-3-onePolyethylene glycol 400
go.drugbank.com/drugs/DB11077ApprovedInvestigationalIt is very hydrophilic, which renders it a useful ingredient in drug formulations to augment the solubility and bioavailability of weakly water-soluble drugs. … Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain various derivatives and have various functions.
Mixtures: Redness reliever and Lubricant, Systane Day and Night Value PackProducts: Foster and Thrive Dry Eye ReliefZolmitriptan
go.drugbank.com/drugs/DB00315ApprovedInvestigational[A462, L12978] [Sumatriptan] was the first triptan to be developed, but had poor oral bioavailability and lipophilicity. … [A193797] Zolmitriptan was first approved by the FDA for sale by Zeneca Pharmaceuticals under the trade name Zomig® on November 25, 1997.
Categories: Serotonin-1b and Serotonin-1d Receptor Agonist, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: ZOMIG 2.5MG, ZOLMITRIPTAN AL 2.5MGMirtazapine
go.drugbank.com/drugs/DB00370ApprovedInvestigationalIt may improve the symptoms of neurological disorders, reverse weight loss caused by medical conditions, improve sleep, and prevent nausea and vomiting after surgery.[A177811] … [A177946] This drug was first manufactured by Organon Inc., and received FDA approval in 1997 for the treatment of major depressive disorder.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: Nu-mirtazapine, Co MirtazapineCortisone acetate
go.drugbank.com/drugs/DB01380ApprovedInvestigational, hematologic, neoplastic, edematous, and gastrointestinal diseases and disorders. … Cortisone acetate was first isolate in 1935 and became more widely researched in 1949.
Categories: Hormones, Hormone Substitutes, and Hormone AntagonistsProducts: Cortone Tab 25mg, Cortone Sus 50mg/ml