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Displaying results 861 - 870 of 10000 in total
  1. Indication

    Bleeding caused by Hemophilia A Without Inhibitor

    go.drugbank.com/conditions/DBCOND0170627
    Drugs: Fitusiran · Marstacimab
    Synonyms: Bleeding caused by Hemophilia A Without Inhibitor
  2. Indication

    Proteinuria caused by Primary Immunoglobulin A Nephropathy

    go.drugbank.com/conditions/DBCOND0168683
    Drugs: Sibeprenlimab
    Synonyms: Proteinuria caused by Primary Immunoglobulin A Nephropathy
  3. Drug

    Terfenadine

    go.drugbank.com/drugs/DB00342
    ApprovedWithdrawn

    In the U.S., Terfenadine was superseded by fexofenadine in the 1990s due to the risk of cardiac arrhythmia caused by QT interval prolongation.

    Synonyms: (RS)-1-(4-tert-butylphenyl)-4-{4-[hydroxy(diphenyl)methyl]piperidin-1-yl}-butan-1-olInternational brands: Terfenadin AL
  4. Drug

    Magnesium

    go.drugbank.com/drugs/DB14513
    ApprovedInvestigational

    [A39559] Several factors and common behaviours reduce the availability of magnesium in the diet such as food processing and cooking vegetables (which are normally a rich source of magnesium).[A39559] … Magnesium is classified as an alkaline earth metal and has 2 hydration shells.

    Mixtures: One A Day Tab, Extra Once A DayProducts: MAGNEROT A 500 BEUTEL, MAGNEROT A 120 KAUTABL
  5. Drug

    Zinc

    go.drugbank.com/drugs/DB01593
    ApprovedInvestigational

    a marker of these diseases [L2097]. … A metallic element of atomic number 30 and atomic weight 65.38.

    Mixtures: A + Zinc, A/o-26 - CapletProducts: Port A Mins Super Zinc 15, Port A Mins Super Zinc 30
  6. Drug

    Vidarabine

    go.drugbank.com/drugs/DB00194
    ApprovedWithdrawn

    A nucleoside antibiotic isolated from Streptomyces antibioticus. … It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the

    Synonyms: 9-β-D-arabinofuranosyl-9H-purin-6-amine, 9-β-D-arabinofuranosyladenineInternational brands: Arasena-A
  7. Drug

    Malathion

    go.drugbank.com/drugs/DB00772
    Approved

    Malathion is a parasympathomimetic organophosphate compound that is used as an insecticide for the treatment of head lice. … Malathion is an irreversible cholinesterase inhibitor and has low human toxicity.

    Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 SubstratesSynonyms: O,O-dimethyl S-(1,2-bis(ethoxycarbonyl)ethyl), O,O-dimethyl S-1,2-di(ethoxycarbamyl)ethyl
  8. Drug

    House dust

    go.drugbank.com/drugs/DB10345
    Approved

    House dust allergenic extract is used in allergenic testing.

    Products: A. Dust, AP House Dust Mix
  9. Indication

    Ankle spasticity following a stroke or traumatic brain injury

    go.drugbank.com/conditions/DBCOND0133858
    Drugs: Clostridium botulinum
    Synonyms: Ankle spasticity following a stroke or traumatic brain injury
  10. Target

    3-hydroxy-3-methylglutaryl-coenzyme A reductase

    go.drugbank.com/bio_entities/BE0000574
    TargetEnzymeHumans

    HMGCR is the main target of statins, a class of cholesterol-lowering drugs (PubMed:11349148, PubMed:18540668, PubMed:36745799) … Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular

    Polypeptides: 3-hydroxy-3-methylglutaryl-coenzyme A reductaseFunction: coenzyme A binding