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Dipyridamole
go.drugbank.com/drugs/DB00975ApprovedInvestigationalA phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin.
Mixtures: AGGRENOX ® CAPSULAS DE LIBERACION RETARDADACategories: P-glycoprotein inhibitors, P-glycoprotein substratesEthinylestradiol
go.drugbank.com/drugs/DB00977ApprovedInvestigationalEthinylestradiol was first synthesized in 1938 by Hans Herloff Inhoffen and Walter Hohlweg at Schering. It was developed in an effort to create an estrogen with greater oral bioavailability. These properties were achieved by the substitu...
Mixtures: Alyacen 7/7/7, Alyacen 7/7/7Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesCyclopentolate
go.drugbank.com/drugs/DB00979ApprovedA parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia.
Mixtures: Mydriatic-3Synonyms: 2-(dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate, 2-phenyl-2-(1-hydroxycyclopentyl)ethanoic acid β-(dimethylamino)ethyl esterFrovatriptan
go.drugbank.com/drugs/DB00998ApprovedFrovatriptan is a triptan drug developed by Vernalis for the treatment of migraine headaches, in particular those associated with menstruation.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: NEWART 2.5 MG TABLET, 3 ADET, NEWART 2.5 MG TABLET, 6 ADETTioconazole
go.drugbank.com/drugs/DB01007ApprovedTioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. … Tioconazole is an imidazole antifungal used to treat fungal and yeast infections. Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus".
Mixtures: GYNOMAX L VAJINAL OVUL, 7 ADET, Gynecure Com.pk.vag Ont6.5%vulvar Crm1% W/wCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP3A InhibitorsBusulfan
go.drugbank.com/drugs/DB01008ApprovedInvestigationalBusulfan is a bifunctional alkylating agent, having a selective immunosuppressive effect on bone marrow. It is not a structural analog of the nitrogen mustards. … According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), busulfan is listed as a known carcinogen.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesSynonyms: 1, 4-Bis[methanesulfonoxy]butaneMetyrapone
go.drugbank.com/drugs/DB01011ApprovedInvestigationalIt is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of cushing syndrome.
Categories: Cytochrome P-450 CYP2A6 Inhibitors, Cytochrome P-450 CYP3A InducersBethanechol
go.drugbank.com/drugs/DB01019ApprovedBethanechol is a synthetic ester that was initially synthesized in 1935. … system is necessary.
Synonyms: 2-(carbamoyloxy)-N,N,N-trimethylpropan-1-aminium, carbamyl-β-methylcholineProducts: ยูโคลีน (5 มิลลิกรัม)Isosorbide mononitrate
go.drugbank.com/drugs/DB01020ApprovedInvestigationalIsosorbide mononitrate is an organic nitrate with vasodilating properties. … Like other organic nitrates, isosorbide mononitrate acts as a prodrug for its active metabolite, [nitric oxide], which mediates the therapeutic action of isosorbide mononitrate.
Synonyms: IS 5-MN, IS-5-MNProducts: IMOCARD SR, SORBINATE SR 60 TABLETSPhylloquinone
go.drugbank.com/drugs/DB01022ApprovedInvestigational[L33319,L33345] Phylloquinone is a cofactor of the enzyme γ-carboxylase, which modifies and activates precursors to coagulation factors II, VII, IX, and X. … of vitamin K.
Mixtures: Mvc 9+4 Inj, L-SOLUVIT NCategories: Vitamin K