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Displaying results 8691 - 8700 of 10000 in total

Drug
Vosoritide
go.drugbank.com/drugs/DB11928
ApprovedInvestigational
of a condition like achondroplasia. … of a peptidase-resistant formulation has allowed for its use as a viable treatment option in achondroplasia.
Categories: C-type Natriuretic Peptide Analog
Drug
Vaniprevir
go.drugbank.com/drugs/DB11929
Investigational
Vaniprevir has been used in trials studying the treatment and diagnostic of Hepatitis C, Chronic Hepatitis C, Hepatitis C, Chronic, Chronic Hepatitis C Infection, and Chronic Genotype 1 Hepatitis C Virus
Categories: Heterocyclic Compounds, 2-Ring
Drug
Varlilumab
go.drugbank.com/drugs/DB11930
Investigational
Varlilumab has been used in trials studying the treatment of MELANOMA, Skin Ulcer, Burkett's Lymphoma, Mantle cell lymphoma, and Any T-cell Malignancy, among others.
Drug
Abametapir
go.drugbank.com/drugs/DB11932
Approved
[A216183] Topical pediculicides generally lack adequate ovicidal activity,[A216183] including standard-of-care treatments such as [permethrin], and many require a second administration 7-10 days following … Abametapir is a novel pediculicidal metalloproteinase inhibitor used to treat infestations of head lice.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Inhibitors
Drug
Avelumab
go.drugbank.com/drugs/DB11945
ApprovedInvestigational
Avelumab is a human IgG1 lambda monoclonal antibody that binds programmed cell death ligand-1 (PD-L1) to block its interaction with its receptors found on T cells and antigen-presenting cells.
Categories: PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsProducts: BAVENCIO®, BAVENCIO 200 MG/10 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 FLAKON
Drug
PF-04447943
go.drugbank.com/drugs/DB11953
Investigational
PF-04447943 has been investigated for the treatment of Alzheimer's Disease.
Synonyms: 4H-pyrazolo(3,4-d)pyrimidin-4-one, 1,5-dihydro-6-((3S,4S)-4-methyl-1-(2-pyrimidinylmethyl)-3-pyrrolidinyl)-1-(tetrahydro-2H-pyran-4-yl)-, 6-((3S,4S)-4-Methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl)-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo(3,4-d)pyrimidin-4-oneCategories: Heterocyclic Compounds, 1-Ring
Drug
Lomibuvir
go.drugbank.com/drugs/DB11954
Investigational
Lomibuvir has been used in trials studying the treatment of Chronic Hepatitis C Virus and Chronic Hepatitis C Virus Infection.
Categories: Heterocyclic Compounds, 1-Ring
Drug
Brivanib
go.drugbank.com/drugs/DB11958
Investigational
Brivanib is under investigation for the treatment of HepatoCellular Carcinoma. Brivanib has been investigated for the treatment of Solid Tumors, Hepato Cellular Carcinoma (HCC), and Metastatic Colorectal Cancer (MCRC).
Categories: Heterocyclic Compounds, 1-Ring
Drug
Carboxyamidotriazole
go.drugbank.com/drugs/DB11960
Investigational
Carboxyamidotriazole has been used in trials studying the treatment of Lymphoma, Lung Cancer, Breast Cancer, Kidney Cancer, and Ovarian Cancer, among others.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
Drug
Tesevatinib
go.drugbank.com/drugs/DB11973
Investigational
Tesevatinib inhibits the EGF, HER2, and VEGF RTKs, each of which is a target of currently approved cancer therapies. … In addition, tesevatinib inhibits EphB4, an RTK that is highly expressed in many human tumors and plays a role in promoting angiogenesis.
Categories: Heterocyclic Compounds, 2-Ring, Receptor, ErbB-2, antagonists & inhibitors