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HM15912
go.drugbank.com/drugs/DB18266InvestigationalHM15912 is a human glucagon-like peptide-2 analogue linked to a human immunoglobulin Fc fragment.
EB003
go.drugbank.com/drugs/DB18362ExperimentalEB003 is a CRISPR-based sequence-specific antimicrobial (SSAM) targeted against shiga toxin-producing _E. coli_.
Synonyms: Phage-derived, non-replicative delivery vector carrying a DNA payload encoding an RNA-guided nuclease that targets stx genes of Shiga toxin-producing Escherichia coli (STEC)Flutemetamol
go.drugbank.com/drugs/DB15058InvestigationalFlutemetamol is under investigation in clinical trial NCT02353949 (Investigating the Clinical Consequences of Flutemetamol-PET-scanning).
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingIrosustat
go.drugbank.com/drugs/DB02292InvestigationalIrosustat has been investigated for the treatment of Metastatic Breast Cancer and Locally Advanced Breast Cancer.
Synonyms: 6-Oxo-8,9,10,11-Tetrahydro-7h-Cyclohepta[C][1]Benzopyran-3-O-SulfamateCM4620
go.drugbank.com/drugs/DB16466InvestigationalCM4620 (Zegocractin), is under investigation in multiple clinical trials, including NCT04195347 (pancreatitis due to asparaginase), NCT03709342 (PK/PD study in acute pancreatitis), NCT03401190 and NCT04681066
Categories: Heterocyclic Compounds, 1-RingSynonyms: BENZAMIDE, N-(5-(6-CHLORO-2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)-2-PYRAZINYL)-2-FLUORO-6-METHYL-, N-(5-(6-CHLORO-2,2-DIFLUOROBENZO(D)(1,3)DIOXOL-5-YL)PYRAZIN-2-YL)-2-FLUORO-6-METHYLBENZAMIDEBasimglurant
go.drugbank.com/drugs/DB11833InvestigationalBasimglurant has been used in trials studying the diagnostic and treatment of Depression, Fragile X Syndrome, and Major Depressive Disorder.
Categories: Heterocyclic Compounds, 1-RingZD-6126
go.drugbank.com/drugs/DB11872InvestigationalZD6126 has been used in trials studying the treatment of Kidney Neoplasms, Colorectal Neoplasms, Metastases, Neoplasm, and Carcinoma, Renal Cell.
Lomibuvir
go.drugbank.com/drugs/DB11954InvestigationalLomibuvir has been used in trials studying the treatment of Chronic Hepatitis C Virus and Chronic Hepatitis C Virus Infection.
Categories: Heterocyclic Compounds, 1-RingDinaciclib
go.drugbank.com/drugs/DB12021InvestigationalDinaciclib has been used in trials studying the treatment of rrMM, rrCLL, rrDLBCL, Solid Tumors, and Solid Neoplasm, among others.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingGanetespib
go.drugbank.com/drugs/DB12047InvestigationalGanetespib is under investigation for the treatment of BREAST CANCER, Small Cell Lung Cancer, Acute Myeloid Leukaemia, and Myelodysplastic Syndrome.
Categories: Heterocyclic Compounds, 1-Ring