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Displaying results 871 - 880 of 10000 in total
  1. Drug

    Agalsidase alfa

    go.drugbank.com/drugs/DB15874
    ApprovedInvestigational

    While patients generally do not experience a clinically significant difference in outcomes between the two drugs, some patients may experience greater benefit with agalsidase beta. … [A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa, after a contamination event in 2009.

    Products: REPLAGAL CONCENTRATE FOR SOLUTION FOR INFUSION 1 MG/ML
  2. Drug

    Idursulfase

    go.drugbank.com/drugs/DB01271
    ApprovedInvestigational

    Idursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. Idursulfase is produced by recombinant DNA technology in a human cell line. … The enzyme activity of idursulfase is dependent on the post-translational modification of a specific cysteine to formylglycine.

    Products: ELAPRASE SOLUTION FOR INTRAVENOUS INFUSION, Elaprase (TM) Solution for Intravenous Infusion 2mg/ ml
  3. Drug

    Doripenem

    go.drugbank.com/drugs/DB06211
    ApprovedWithdrawn

    The FDA revised the doripenem label in 2014 to include a warning against use in ventilator-associated pneumonia and to reiterate its safety and efficacy for its approved indications. … Doripenem injection was approved by the FDA in 2007 to treat complicated urinary tract and intra-abdominal infections.

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Powder for Injection 500mg, DORIBAX 500 MG (Doripenem) for Injection
  4. Drug

    Calcitriol

    go.drugbank.com/drugs/DB00136
    ApprovedInvestigationalNutraceutical

    It is also available in topical form for the treatment of mild to moderate plaque psoriasis in adults. … It is produced in the body after series of conversion steps of 7-dehydrocholesterol from exposure to UV light. 7-dehydrocholesterol is converted to [DB00169] (vitamin D3) in the skin, which is then converted

    Categories: Antipsoriatics for Topical UseProducts: RO-CAL 0.25mcg, K-LAM
  5. Drug

    Zinc acetate

    go.drugbank.com/drugs/DB14487
    ApprovedInvestigational

    Mixtures: OMEGA PLUS EMULSION FOR INFUSION, OMEGA SPECIAL EMULSION FOR INFUSIONCategories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use
  6. Drug

    Magnesium acetate

    go.drugbank.com/drugs/DB13996
    Approved

    Synonyms: acetic acid magnesium salt, Mg(II) acetateMixtures: Plasma-lyte 56 5% Dextrose Inj, Lypholyte Multi-electrolyte Conc Inj
  7. Drug

    Tetrofosmin

    go.drugbank.com/drugs/DB11180
    Approved

    Tetrofosmin is used in conjunction with technetium Tc-99m as a radiopharmaceutical.[A7788] … Tetrofosmin was developed to overcome the non-target uptake of radioligands by the generation of hetero-atomic compounds.

    Mixtures: Tetrofosmin ROTOP 0,23 mg Kit für ein radioaktives ArzneimittelProducts: MYOVIEW POWDER FOR INJECTION, MYOVIEW FOR INJECTION 0.23 mg/vial
  8. Drug

    Human thrombin

    go.drugbank.com/drugs/DB11571
    ApprovedInvestigational

    Human thrombin is a sterile solution, pH 6.8-7.2, containing highly purified human thrombin for the activation of clotting. … In particular, while human thrombin products are made from pooled human source plasma, recombinant thrombin is a human coagulation protein produced via recombinant DNA technology from a genetically modified

    Mixtures: ARTISS SOLUTIONS FOR SEALANT, DEEP FROZEN, EVICEL Fibrin Sealant (Human) Solution, 50-90 mg/ml, 800-1200 IU/mlProducts: THROMBIRAAS1000 UI
  9. Drug

    Torasemide

    go.drugbank.com/drugs/DB00214
    ApprovedInvestigational

    [A319] Torasemide was first approved for clinical use by the FDA in 1993.[L5257] … Torasemide is a high-ceiling loop diuretic.[A174463] Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent.

    Categories: Antihypertensive Agents Indicated for Hypertension, Non Potassium Sparing DiureticsSynonyms: N-(((1-Methylethyl)amino)carbonyl)-4-((3-methylphenyl)amino)-3-pyridinesulfonamide
  10. Drug

    Prilocaine

    go.drugbank.com/drugs/DB00750
    ApprovedInvestigational

    A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)

    Mixtures: PRESTIGE® NF, ACAT SUK Kit (Accelerated COVID-19 Antibody Test Single Use Kit)Synonyms: alpha-n-Propylamino-2-methylpropionanilide, N-(2-Methylphenyl)-2-(propylamino)propanamide