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PD-168393
go.drugbank.com/drugs/DB07662ExperimentalPD-168393 is an epidermal growth factor receptor inhibitor.
PF-04447943
go.drugbank.com/drugs/DB11953InvestigationalPF-04447943 has been investigated for the treatment of Alzheimer's Disease.
PF-00446687
go.drugbank.com/drugs/DB12517InvestigationalPF-00446687 has been investigated for the treatment of Erectile Dysfunction.
PD-98059
go.drugbank.com/drugs/DB17042ExperimentalPD-98059 is an inhibitor of MAP-kinase kinase activation.[A253072]
Inotuzumab ozogamicin
go.drugbank.com/drugs/DB05889ApprovedInvestigationalInotuzumab ozogamicin is an antibody-drug conjugate consisting of a humanized IgG4 kappa CD22-targeting monoclonal antibody covalently attached to calicheamicin derivative, N-acetyl-gamma-calicheamicin dimethylhydrazide. The antibody por...
Categories: P-glycoprotein substrates, P-glycoprotein substrates with a Narrow Therapeutic IndexIvabradine
go.drugbank.com/drugs/DB09083ApprovedInvestigationalIvabradine, brand name Corlanor, was approved by the FDA in April 2015 for the treatment of chronic heart failure in patients with an ejection fraction of ≤35%, in sinus rhythm with resting heart rate
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: IVABRADINA DOC GENERICIElagolix
go.drugbank.com/drugs/DB11979ApprovedInvestigationalFood and Drug Administration (FDA) approved AbbVie's elagolix under the brand name Orilissa as the first and only oral gonadotropin-releasing hormone (GnRH) antagonist specifically developed for women
Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsEvinacumab
go.drugbank.com/drugs/DB15354ApprovedInvestigationalevinacumab became the first-and-only inhibitor of ANGPTL3 to receive FDA approval after it was granted approval for the adjunctive treatment of homozygous familial hypercholesterolemia (HoFH) under the brand
PD-173952
go.drugbank.com/drugs/DB17041ExperimentalPD-173952 is a potent Myt1 kinase inhibitor.[A253067]