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Robenidine
go.drugbank.com/drugs/DB11542ExperimentalVet approvedRobenidine is used to control coccidiosis, a lethal infection in poultry which has shown a significant economic burden. … Farmers alternate the use of robenidine with other antimicrobial agents in order to maintain effectiveness by slowing the development of antimicrobial resistance.
Saruparib
go.drugbank.com/drugs/DB18982InvestigationalSaruparib is under investigation in clinical trial NCT06380751 (Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in Hr-positive, Her2-negative
Synonyms: 2-Pyridinecarboxamide, 5-[4-[(7-ethyl-5,6-dihydro-6-oxo-1,5-naphthyridin-3-yl)methyl]-1-piperazinyl]-N-methyl-, 5-{4-[(7-ethyl-5,6-dihydro-6-oxo-1,5-naphthyridin-3- yl)methyl]piperazin-1-yl}-N-methylpyridine-2- carboxamideSirpiglenastat
go.drugbank.com/drugs/DB17536InvestigationalIt is under investigation in clinical trial NCT04471415 (Study to Investigate DRP-104 in Adults With Advanced Solid Tumors).
Synonyms: L-norleucine, n-acetyl-l-tryptophyl-6-diazo-5-oxo-, 1-methylethyl ester, Propan-2-yl (2s)-2-((n-acetyl-l-tryptophyl)amino)-6-diazo-5-oxohexanoateZibrofusidic acid
go.drugbank.com/drugs/DB20799InvestigationalZibrofusidic acid is under investigation in clinical trial NCT00626795 (Efficacy, Safety, and Tolerability of TD1414 2% Cream in Impetigo and Secondarily Infected Traumatic Lesions (SITL)).
Evixapodlin
go.drugbank.com/drugs/DB21520InvestigationalEvixapodlin is under investigation in clinical trial NCT04049617 (Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of Evixapodlin (Formerly GS-4224) in Participants With Advanced
Amperozide
go.drugbank.com/drugs/DB08927ExperimentalAlternatively, amperozide's main use lies in veterinary medicine, where it is typically employed to minimize aggression and stress in intensively farmed pigs. … Investigations regarding the use of the agent revolved primarily around its capability for treating schizophrenia in humans even though the drug was ultimately never clinically adopted for this indication
Lemuteporfin
go.drugbank.com/drugs/DB04980InvestigationalLemuteporfin, under development by QLT Incorporated, is a benzoporphyrin-derived chlorin-like photosensitizer. It is intended for the treatment of beign prostatic hyperplasia.
Macozinone
go.drugbank.com/drugs/DB14821InvestigationalMacozinone is under investigation in clinical trial NCT03036163 (Phase 1 Study of PBTZ169).
JQ1
go.drugbank.com/drugs/DB17021ExperimentalFirst-in-class potent and selective inhibitor of the BRD4 signaling pathway.[A252967]
NKX101
go.drugbank.com/drugs/DB18131InvestigationalNKX101 is an investigational allogeneic chimeric antigen receptor (CAR)-natural killer cell therapy.
Synonyms: a fourth generation activating chimeric receptor (ACR) natural killer (NK) cell therapy engineered with an NKG2D ACR, OX40 costimulatory domain, CD3zeta signaling moiety, and membrane bound IL-15 (mb-IL15