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Ceftiofur
go.drugbank.com/drugs/DB11485ExperimentalVet approvedIt is marketed by pharmaceutical company Zoetis as Excenel, and is the active ingredient in that company's Specramast LC (lactating cow formula) product. … Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary medicine.
Categories: Heterocyclic Compounds, 2-RingNalorphine
go.drugbank.com/drugs/DB11490ExperimentalVet approvedNalorphine is a mixed opioid agonist–antagonist. … It is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid dependence.
Categories: Heterocyclic Compounds with 4 or More RingsSarafloxacin
go.drugbank.com/drugs/DB11491ApprovedVet approvedWithdrawnSarafloxacin is a quinolone antibiotic drug, which was discontinued by its manufacturer, Abbott Laboratories, before receiving approval for use in the US or Canada.
Categories: 4-Quinolones, Cytochrome P-450 CYP1A2 Inhibitors2-mercaptobenzothiazole
go.drugbank.com/drugs/DB11496ApprovedVet approvedSynonyms: 2-MBT, 2-BenzothiazolethiolSalts: Sodium 2-mercaptobenzothiazoleCaramiphen
go.drugbank.com/drugs/DB11504ExperimentalVet approvedCaramiphen is a cholinergic antagonist used in Parkinson's disease. … Additionally, it is used, in combination with [phenylpropanolamine], as a cough suppressant and nasal decongestant for the symptomatic treatment of seasonal respiratory conditions.
Difloxacin
go.drugbank.com/drugs/DB11511ExperimentalVet approvedDifloxacin is a synthetic fluoroquinolone used in veterinary. As an antibacterial, it presents a broad bactericidal spectrum and its effects are dependent on its concentration. … However, it presents a reduced efficacy when compared to other fluoroquinolone antibacterials.
Categories: 4-Quinolones, Cytochrome P-450 SubstratesDihydrostreptomycin
go.drugbank.com/drugs/DB11512ApprovedVet approvedWithdrawnDihydrostreptomycin is an aminoglycoside antibiotic. In humans, the use of dihydrostreptomycin has been associated with ototoxicity.
Synonyms: N,N'''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-a-L-glucopyranosyl]-3-C-(hydroxymethyl)-a-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine, N,N'''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-α-L-glucopyranosyl]-3-C-(hydroxymethyl)-α-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidineDithiazanine
go.drugbank.com/drugs/DB11516ApprovedVet approvedWithdrawnDithiazanine is a highly potent anthelmintic, introduced in 1959 for the treatment of strongyloid worms and whipworms. However, its use is severely limited due to its toxicity. … Dithiazanine iodide has been withdrawn from the market in countries such as France in Italy, but it may remain available in others.[A254427,L44032]
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingElbasvir
go.drugbank.com/drugs/DB11574ApprovedElbasvir is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C, an infectious liver disease caused by infection with hepatitis C virus (HCV). … Elbasvir is available as a fixed-dose combination product with [grazoprevir] (tradename: Zepatier) used for the treatment of chronic hepatitis C.
Mixtures: ZEPATIER® TABLETAS RECUBIERTASCategories: P-glycoprotein inhibitors, P-glycoprotein substratesIndigotindisulfonic acid
go.drugbank.com/drugs/DB11577ApprovedInvestigationalIndigotindisulfonic acid is a blue-colored dye with a variety of uses. … [A32490,A32491,A32492,L2222] Its salt form, indigotindisulfonate sodium, is also known as indigo carmine, indigotine or FD&C Blue #2.
Synonyms: 2-(1,3-Dihydro-3-oxo-5-sulpho-2H-indol-2-ylidene)-3-oxoindoline-5-sulphonic acid, FD&C Blue #2Categories: Heterocyclic Compounds, 2-Ring, Compounds used in a research, industrial, or household setting