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Verdinexor
go.drugbank.com/drugs/DB12207InvestigationalKpt 335 is under investigation in clinical trial NCT02431364 (Trial of Safety and Tolerability of Oral Verdinexor (Verdinexor) in Healthy Adults).
Categories: Heterocyclic Compounds, 1-RingPSI-697
go.drugbank.com/drugs/DB12211InvestigationalPSI-697 has been used in trials studying the treatment of Scleritis.
Categories: P-Selectin, Heterocyclic Compounds, 2-RingBergapten
go.drugbank.com/drugs/DB12216InvestigationalBergapten is under investigation in clinical trial NCT00533195 (Comparison of UVA1 Phototherapy Versus Photochemotherapy for Patients With Severe Generalized Atopic Dermatitis).
Synonyms: 5 methoxypsoralen, 5-methoxypsoralenCategories: Cytochrome P-450 CYP3A Inhibitors, Heterocyclic Compounds, 1-RingLurtotecan
go.drugbank.com/drugs/DB12222InvestigationalLurtotecan is under investigation in clinical trial NCT00022594 (Liposomal Lurtotecan in Treating Patients With Metastatic or Locally Recurrent Head and Neck Cancer).
Beclabuvir
go.drugbank.com/drugs/DB12225InvestigationalBeclabuvir has been used in trials studying the treatment of Hepatitis C, Chronic.
Categories: Heterocyclic Compounds, 2-RingTelcagepant
go.drugbank.com/drugs/DB12228InvestigationalIt is an antagonist of the receptor for calcitonin gene-related peptide (CGRP), a primary neuropeptide involved in the pathophysiology of migraine.
Categories: Heterocyclic Compounds, 1-RingCerlapirdine
go.drugbank.com/drugs/DB12229InvestigationalCerlapirdine has been investigated for the treatment of Alzheimer Disease.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingTemefos
go.drugbank.com/drugs/DB12231InvestigationalDiphos has been used in trials studying the treatment of Plasmodium Falciparum Malaria.
Categories: Compounds used in a research, industrial, or household settingAZD-7762
go.drugbank.com/drugs/DB12242InvestigationalAZD7762 has been investigated for the treatment of Cancer, Solid Tumors, and Advanced Solid Malignancies.
Categories: Heterocyclic Compounds, 1-RingTriclabendazole
go.drugbank.com/drugs/DB12245ApprovedInvestigational[FDA label, L5452] Fascioliasis is a parasitic infection often caused by the helminth, _Fasciola hepatica_, which is also known as “the common liver fluke” or “the sheep liver fluke” or by _Fasciola … Triclabendazole was previously used in the treatment of fascioliasis in livestock, but is now approved for human use.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 Substrates