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Pevonedistat
go.drugbank.com/drugs/DB11759InvestigationalPevonedistat has been used in trials studying the treatment of Lymphoma, Solid Tumors, Multiple Myeloma, Hodgkin Lymphoma, and Metastatic Melanoma, among others.
Categories: Heterocyclic Compounds, 1-RingImidapril
go.drugbank.com/drugs/DB11783InvestigationalImidapril has been investigated for the treatment of Kidney, Polycystic, Autosomal Dominant.
Categories: Heterocyclic Compounds, 1-RingProducts: TANATRIL TABLETS 5 mg, ทานาทริล 5 มก. ชนิดเม็ดCapmatinib
go.drugbank.com/drugs/DB11791ApprovedInvestigationalCapmatinib is a small molecule kinase inhibitor targeted against c-Met (a.k.a. hepatocyte growth factor receptor [HGFR]), a receptor tyrosine kinase that, in healthy humans, activates signaling cascades … [A199122] This co-occurrence has made c-Met a desirable target in the treatment of NSCLC.
Categories: MATE 2-K Inhibitors, MATE 1 InhibitorsNiraparib
go.drugbank.com/drugs/DB11793ApprovedInvestigational[L43277] Niraparib is selective towards PARP-1 and PARP-2. … [L43277] Niraparib was approved by the European Commission on November 16, 2017 [L43742] and by Health Canada on June 27, 2019.
Categories: MATE 1 Substrates with a Narrow Therapeutic Index, MATE 2 Substrates with a Narrow Therapeutic IndexErtugliflozin
go.drugbank.com/drugs/DB11827ApprovedInvestigationalErtugliflozin is a sodium-dependent glucose cotransporter-2 (SGLT2) inhibitor used to treat type II diabetes mellitus. It works to block glucose reabsorption from the glomerulus. … [A261951, L1132] It was also approved by the European Commission in March 2018.[L48621]
Synonyms: (1S,2S,3S,4R,5S)-5-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol, 1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-β-L-idopyranoseCategories: P-glycoprotein substrates, Sodium-Glucose Transporter 2 InhibitorsPrulifloxacin
go.drugbank.com/drugs/DB11892InvestigationalPrulifloxacin has been investigated for the treatment of Urinary Tract Infection.
Categories: 4-Quinolones, Heterocyclic Compounds, 1-RingPridopidine
go.drugbank.com/drugs/DB11947InvestigationalPridopidine has been used in trials studying the treatment of Huntington's Disease.
Categories: Heterocyclic Compounds, 1-RingIlaprazole
go.drugbank.com/drugs/DB11964InvestigationalIlaprazole has been investigated in Helicobacter Infections.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: NOLTEC 10 MG GASTRO-REZİSTAN TABLET, 7 ADETCarbon black
go.drugbank.com/drugs/DB11980InvestigationalProduced by the incomplete combustion of hydrocarbons, carbon black is an insoluble pigment [A263396] with demonstrated adverse effects on pulmonary function.
Synonyms: D&C black no. 2, D&C BLACK NO. 2 [II]Elamipretide
go.drugbank.com/drugs/DB11981ApprovedInvestigational[A274436] Elamipretide is a synthetic tetrapeptide that selectively binds to cardiolipin, a phospholipid in the inner mitochondrial membrane. … Elamipretide is a mitochondrial cardiolipin binder being investigated for diseases involving mitochondrial dysfunction.
Categories: MATE 1 Inhibitors