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Displaying results 8861 - 8870 of 10000 in total
  1. Drug

    Elamipretide

    go.drugbank.com/drugs/DB11981
    ApprovedInvestigational

    [A274436] Elamipretide is a synthetic tetrapeptide that selectively binds to cardiolipin, a phospholipid in the inner mitochondrial membrane. … Elamipretide is a mitochondrial cardiolipin binder being investigated for diseases involving mitochondrial dysfunction.

    Categories: MATE 1 Inhibitors
  2. Drug

    Nirogacestat

    go.drugbank.com/drugs/DB12005
    ApprovedInvestigational

    Nirogacestat is a small-molecule gamma-secretase inhibitor that was investigated as a potential treatment for desmoid tumors. … DeFi trial, where a confirmed objective response rate was observed to be 41% compared to 8% with the placebo.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
  3. Drug

    Ozagrel

    go.drugbank.com/drugs/DB12017
    Investigational

    Ozagrel has been used in trials studying the treatment of Dry Eye Syndromes.

    Categories: Thromboxane-A Synthase, antagonists & inhibitors
  4. Drug

    Evatanepag

    go.drugbank.com/drugs/DB12022
    Investigational

    Evatanepag has been used in trials studying the treatment of Tibial Fractures.

    Categories: Heterocyclic Compounds, 1-Ring
  5. Drug

    Crenigacestat

    go.drugbank.com/drugs/DB12050
    Investigational

    Crenigacestat has been used in trials studying the treatment and basic science of LYMPHOMA, Neoplasms, Solid Tumor, COLON CANCER, and BREAST CANCER, among others.

    Categories: Heterocyclic Compounds, 2-Ring
  6. Drug

    Pardoprunox

    go.drugbank.com/drugs/DB12061
    Investigational

    Pardoprunox is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  7. Drug

    Volasertib

    go.drugbank.com/drugs/DB12062
    Investigational

    Volasertib has been used in trials studying the treatment of Leukemia, Neoplasms, Leukemia, Myeloid, Acute, Myelodysplastic Syndromes, and Leukemia, Monocytic, Acute, among others.

    Categories: Heterocyclic Compounds, 2-Ring
  8. Drug

    Vabicaserin

    go.drugbank.com/drugs/DB12071
    Investigational

    Vabicaserin has been used in trials studying the health services research and treatment of Schizophrenia.

    Categories: Serotonin 5-HT2 Receptor Agonists, Serotonin 5-HT2C Receptor Agonists
  9. Drug

    Sultamicillin

    go.drugbank.com/drugs/DB12127
    ApprovedWithdrawn

    Sultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated Pneumonia and Chronic Obstructive Pulmonary Disease (COPD).

    Categories: Penicillin G, Heterocyclic Compounds, 2-RingProducts: BACTESUL 1 G/ 5 ML, BACMICINE® 250 MG / 5 ML
  10. Drug

    Dilmapimod

    go.drugbank.com/drugs/DB12140
    Investigational

    Dilmapimod (SB-681323) is a p38 MAP-kinase inhibitor that has potential uses in inflammatory conditions such as RA (Rheumatoid Arthritis).

    Categories: Heterocyclic Compounds, 1-Ring