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Displaying results 881 - 890 of 10000 in total
  1. Target

    Protein RecA

    go.drugbank.com/bio_entities/BE0001235
    TargetMycobacterium smegmatis (strain ATCC 700084 / mc(2)155)

    Required for homologous recombination (HR) and the bypass of mutagenic DNA lesions (double strand breaks, DSB) by the SOS response. Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of si...

    Polypeptides: Protein RecA
  2. Target

    Proteasome activator complex subunit 1

    go.drugbank.com/bio_entities/BE0008976
    TargetHumans

    The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome

    Polypeptides: Proteasome activator complex subunit 1Synonyms: 11S regulator complex subunit alpha
  3. Target

    MHC class II protein complex

    go.drugbank.com/bio_entities/BE0011001
    TargetHumans

  4. Indication

    Tuberous Sclerosis Complex with Subependymal Giant Cell Astrocytoma

    go.drugbank.com/conditions/DBCOND0025535
    Drugs: Everolimus
    Synonyms: Tuberous Sclerosis Complex with Subependymal Giant Cell Astrocytoma
  5. Drug

    Zinc gluconate

    go.drugbank.com/drugs/DB11248
    ApprovedInvestigationalVet approved

    Studies show that zinc may be better absorbed in humans in the gluconate form [A32412], [L2105], however, results from other studies may vary. … More information about Zinc (in its natural form) is available at [DB01593].

    Mixtures: Dermamed Nutrition for troubled skin, Children's Chew Multi & Min TabProducts: Zinc Complex 30mg Tab
  6. Drug

    Insulin glargine

    go.drugbank.com/drugs/DB00047
    ApprovedInvestigational

    As of 2015, insulin glargine was reformulated by Sanofi as the product Toujeo in an extra-concentrated form containing 300IU/mL (compared to 100IU/mL contained in Lantus). … Insulin glargine is also available as the biosimilar, or "follow-on" product, Basaglar in the US and as Abasaglar in the EU.

    Mixtures: Soliqua SoloStar 100units/mL+33mcg/mL solution for injection in a pre-filled pen, Soliqua SoloStar 100units/mL+50mcg/mL solution for injection in a pre-filled penCategories: Drugs Used in Diabetes, Complex Mixtures
  7. Target

    Protein RecA

    go.drugbank.com/bio_entities/BE0001257
    TargetDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)

    Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA caus...

    Polypeptides: Protein RecA
  8. Target

    Protein RecA

    go.drugbank.com/bio_entities/BE0003084
    TargetShigella flexneri

    Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA caus...

    Polypeptides: Protein RecA
  9. Target

    Copper chaperone for superoxide dismutase

    go.drugbank.com/bio_entities/BE0005815
    CarrierTargetHumans

    Delivers copper to copper zinc superoxide dismutase (SOD1)

    Polypeptides: Copper chaperone for superoxide dismutaseSynonyms: Superoxide dismutase copper chaperone
  10. Target

    Cytochrome c oxidase copper chaperone

    go.drugbank.com/bio_entities/BE0008686
    CarrierHumans

    Copper metallochaperone involved in the assembly of cytochrome c oxidase (respiratory chain complex IV, CIV) (PubMed:15229189, PubMed:19393246, PubMed:31903891, PubMed:35750769). … Binds two copper ions and delivers them to metallochaperones SCO1 and SCO2, which co-chaperone the copper ions to the Cu(A) site on the cytochrome c oxidase subunit II (MT-CO2/COX2), and to metallochaperone

    Polypeptides: Cytochrome c oxidase copper chaperoneFunction: copper chaperone activity