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Arsthinol
go.drugbank.com/drugs/DB08928ExperimentalArsthinol (INN) is an antiprotozoal agent that was first synthesized by Ernst A.H. Friedheim in 1949 via the complexing of acetarsol with 2,3-dimercaptopropanol. … It has since been demonstrated that the agent possesses activity against amoebas and yaws.
Elsubrutinib
go.drugbank.com/drugs/DB18850InvestigationalElsubrutinib is under investigation in clinical trial NCT04451772 (A Study of the Safety of Oral Elsubrutinib Capsules and Oral Upadacitinib Tablets Given Alone or in Combination (ABBV-599) for Adult Participants … With Moderately to Severely Active Systemic Lupus Erythematosus to Assess Change in Disease State).
Synonyms: (s)-4-(1-acryloylpiperidin-3-yl)-1h-indole-7-carboxamide, 4-((3s)-1-(prop-2-enoyl)-piperidin-3-yl)-1h-indole-7-carboxamideKOSN-1724
go.drugbank.com/drugs/DB13078InvestigationalKOSN-1724 is under investigation in clinical trial NCT01379287 (Dose-Escalation Safety and Pharmacokinetic Study of Iso-Fludelone in Patients With Advanced Solid Tumors).
Resolvin E1
go.drugbank.com/drugs/DB13105InvestigationalResolvin E1 (RX 10001) is under investigation in clinical trial NCT00941018 (Single and Multiple Ascending Oral Dose Study of Resolvin E1 in Healthy Volunteers).
CA-074 methyl ester
go.drugbank.com/drugs/DB07223ExperimentalCA-074 methyl ester (CA-074Me) is a cell-permeable cathepsin B inhibitor. It is converted by cellular esterases to CA-074.[A258234,A258239]
Synonyms: Methyl N-({(2s,3s)-3-[(propylamino)carbonyl]oxiran-2-Yl}carbonyl)-L-isoleucyl-L-prolinate, L-Proline, N-[[(2S,3S)-3-[(propylamino)carbonyl]oxiranyl]carbonyl]-L-isoleucyl-, methyl esterPolyacrylamide (crosslinked; 2 mole percent bisacrylamide)
go.drugbank.com/drugs/DB14771InvestigationalPolyacrylamide (crosslinked; 2 mole percent bisacrylamide) is under investigation in clinical trial NCT00629083 (Bulking Agents for the Treatment of Stress Urinary Incontinence in Females).
Samelisant
go.drugbank.com/drugs/DB14835InvestigationalSUVN-G3031 is under investigation in clinical trial NCT02342041 (A Study to Investigate the Safety, Tolerability and Pharmacokinetics of SUVN-G3031 in Healthy Subjects).
Gavorestat
go.drugbank.com/drugs/DB16707InvestigationalGavorestat is under investigation in clinical trial NCT04902781 (Clinical Benefit, Safety, PK and PD Study of AT-007 in Pediatric Subjects With Classic Galactosemia).
Synonyms: 2-(4-Oxo-3-((5-(Trifluoromethyl)Benzo[D]Thiazol-2-Yl)Methyl)-3,4-Dihydrothieno[3,4-D]Pyridazin-1-Yl)Acetic AcidDisitamab vedotin
go.drugbank.com/drugs/DB17208InvestigationalDisitamab vedotin is an antibody-drug conjugate drug targeting human epidermal growth factor receptor 2 (HER2). It is currently being investigated for cancers.[A254721]
Ixmyelocel-T
go.drugbank.com/drugs/DB17601InvestigationalIxmyelocel-T is an expanded, autologous multicellular therapy cultured from bone-marrow mononuclear cells. Developed by Vericel Corporation, it is being investigated for cardiomyopathy.