Resolvin E1

DB13105InvestigationalSmall molecule

Resolvin E1 (RX 10001) is under investigation in clinical trial NCT00941018 (Single and Multiple Ascending Oral Dose Study of Resolvin E1 in Healthy Volunteers).

Mechanism: Pharmacologically active on Leukotriene B4 receptor 1 and Chemerin-like receptor 1
Curator reviewed
Formula / weight: C₂₀H₃₀O₅ · 350.455 g/mol (avg)
Also known as: (5S,6Z,8E,10E,12R,14Z,16E,18R)-5,12,18-TRIHYDROXY-6,8,10,14,16-EICOSAPENTAENOIC ACID · 5S,12R,18R-TRIHYDROXY-6Z,8E,10E,14Z,16E-EICOSAPENTAENOIC ACID · 6,8,10,14,16-EICOSAPENTAENOIC ACID, 5,12,18-TRIHYDROXY-, (5S,6Z,8E,10E,12R,14Z,16E,18R)- · RVE1
Code names: J2.218.407E · RX-10001

Resolves to

Compound

UNIIGND3JH08JACAS552830-51-0ChEMBLCHEMBL1742483ChEBI81559PubChem10473088KEGGC18171

Structure

InChIKeyAOPOCGPBAIARAV-OTBJXLELSA-NSMILESCC[C@@H](O)\C=C\C=C/C[C@@H](O)\C=C\C=C\C=C/[C@@H](O)CCCC(O)=O

Targets

Q15722LTB4RQ99788CMKLR1

What you can answer from here — as of August 30, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

1Drug interactionStructured to mechanism, not free text

1Clinical trialPhase, status and sponsor resolved per trial

6+ReferencesStructured and connected to the statements they support

Which drugs share a target with Resolvin E1, and which of those have an active Phase 3 trial?

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