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Nelonicline
go.drugbank.com/drugs/DB19040InvestigationalNelonicline is under investigation in clinical trial NCT01678755 (A Phase 2 Study to Evaluate ABT-126 for the Treatment of Cognitive Deficits in Schizophrenia).
Rezvilutamide
go.drugbank.com/drugs/DB19133InvestigationalRezvilutamide is under investigation in clinical trial NCT05956639 (Comparing a 6-month vs Long-term Course of Rezvilutamide With ADT Plus Chemotherapy in Mhspc).
ADAM I-123
go.drugbank.com/drugs/DB19213InvestigationalADAM I-123 is under investigation in clinical trial NCT01160263 (Study of Dopamine and Serotonin Transporters in Patients With Amyotrophic Lateral Sclerosis and Controls).
Synonyms: Benzenemethanamine, 2-((2-amino-4-(iodo-123i)phenyl)thio)-n,n-dimethyl-Eragidomide
go.drugbank.com/drugs/DB19242InvestigationalEragidomide is under investigation in clinical trial NCT04297124 (A Study to Evaluate the Metabolism and Excretion of [14C]-CC-90009 in Healthy Male Subjects).
Synonyms: 2-(4-chlorophenyl)-n-((2-(2,6-dioxopiperidin-3-yl)-1-oxo-2,3-dihydro-1h-isoindol-5-yl)methyl)-2,2-difluoroacetamideAtilotrelvir
go.drugbank.com/drugs/DB19439InvestigationalAtilotrelvir is under investigation in clinical trial NCT05041907 (Finding Treatments for COVID-19: A Trial of Antiviral Pharmacodynamics in Early Symptomatic COVID-19 (PLATCOV)).
Synonyms: (1R,4S,6S)-N-{(1S)-1-ciano-2-[(3S)-2-oxopirrolidin-3-il]etil}-5-[(2S)-3,3-dimetil-2-(2,2,2-trifluoroacetamido)butanoil]-5-azaespiro[biciclo[2.2.1]heptano-2,1'-ciclopropano]-6-carboxamida, Spiro[2-azabicyclo[2.2.1]heptane-5,1′-cyclopropane]-3-carboxamide, N-[(1S)-1-cyano-2-[(3S)-2-oxo-3-pyrrolidinyl]ethyl]-2-[(2S)-3,3-dimethyl-1-oxo-2-[(2,2,2-trifluoroacetyl)amino]butyl]-, (1S,3S,4R)-Brenetafusp
go.drugbank.com/drugs/DB19441InvestigationalBrenetafusp is under investigation in clinical trial NCT04262466 (Safety and Efficacy of IMC-F106C as a Single Agent and in Combination With Checkpoint Inhibitors).
RO-6870810
go.drugbank.com/drugs/DB15151InvestigationalRO-6870810 is under investigation in clinical trial NCT02308761 (A Study of RO6870810/TEN-010 in Participants With Acute Myeloid Leukemia and Myelodysplastic Syndrome).
Synonyms: 2-[(4S)-6-(4-chlorophenyl)-1,7,8-trimethylthiophenol[3,2-f]1,2,4-triazolo[4,3-a]1,4-diazepin-4-yl]-N-[3-(4-methylpiperazinyl)propyl]acetamide, 6H-THIENO(3,2-F)(1,2,4)TRIAZOLO(4,3-A)(1,4)DIAZEPINE-6-ACETAMIDE, 4-(4-CHLOROPHENYL)-2,3,9-TRIMETHYL-N-(3-(4-METHYL-1-PIPERAZINYL)PROPYL)-, (6S)-SYNB1891
go.drugbank.com/drugs/DB17541Investigational[A256733] SYNB1891 is under investigation in clinical trial NCT04167137 (Safety and Tolerability of SYNB1891 Injection Alone or in Combination With Atezolizumab in Adult Subjects). … SYNB1891 is a live, modified strain of the probiotic _Escherichia coli_ Nissle engineered to produce cyclic di-AMP (CDA), a stimulator of the STING (STimulator of INterferon Genes) pathway.
NBF-006
go.drugbank.com/drugs/DB21770InvestigationalNBF-006 is under investigation in clinical trial NCT03819387 (A Study of NBF-006 in Non-small Cell Lung, Pancreatic, or Colorectal Cancer). … This drug is a proprietary siRNA-based lyophilized lipid nanoparticle (LNP).[A273775, L52905]
Cintirorgon
go.drugbank.com/drugs/DB20916InvestigationalCintirorgon is a small molecule drug. Cintirorgon is under investigation in clinical trial NCT02929862 (Study of LYC-55716 in Adult Subjects With Locally Advanced or Metastatic Cancer).