Search

Displaying results 8911 - 8920 of 10000 in total
  1. Drug

    Omaveloxolone

    go.drugbank.com/drugs/DB12513
    ApprovedInvestigational

    [A257534,A257539] Omaveloxolone acts as an activator of nuclear factor (erythroid-derived 2)-like 2 (Nrf2), a transcription factor that mitigates oxidative stress. … In patients with Friedreich's ataxia, a genetic disease involving mitochondrial dysfunction, the Nrf2 pathway is impaired, and Nrf2 activity is lower.

    Synonyms: Propanamide, N-(2-cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoro-Categories: Cytochrome P-450 CYP2C8 Inducers, Cytochrome P-450 Substrates
  2. Drug

    Iofolastat I-123

    go.drugbank.com/drugs/DB12514
    Investigational

    Iofolastat I-123 is under investigation in clinical trial NCT00992745 (A Phase I Pilot Study Comparing 123I MIP 1072 Versus 111In Capromab Pendetide in Subjects With Metastatic Prostate Cancer).

    Synonyms: Iofolastat i 123, Iofolastat (123 I)
  3. Drug

    BI-671800

    go.drugbank.com/drugs/DB12524
    Investigational

    Bi 671800 has been used in trials studying the treatment of Asthma and Rhinitis, Allergic, Perennial.

    Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Batefenterol

    go.drugbank.com/drugs/DB12526
    Investigational

    Batefenterol has been used in trials studying the treatment of Pulmonary Disease, Chronic Obstructive.

    Categories: Heterocyclic Compounds, 2-Ring, Adrenergic beta-2 Receptor Agonists
  5. Drug

    Lobucavir

    go.drugbank.com/drugs/DB12531
    Investigational

    Lobucavir has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-Ring
  6. Drug

    N-acetylmannosamine

    go.drugbank.com/drugs/DB12536
    Investigational

    N-acetylmannosamine is under investigation for the other of GNE Myopathy.

    Synonyms: N-acetylmannosamine
  7. Drug

    SAR-405838

    go.drugbank.com/drugs/DB12541
    Investigational

    SAR405838 has been used in trials studying the treatment of Neoplasm Malignant.

    Categories: P-glycoprotein substrates, Heterocyclic Compounds, 2-Ring
  8. Drug

    GSK-356278

    go.drugbank.com/drugs/DB12542
    Investigational

    Gsk356278 has been used in trials studying the treatment and basic science of Anxiety Disorders, Huntington Disease, Depressive Disorder, Huntingtons Disease, and Depressive Disorder, Major, among others.

    Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Pyrazoloacridine

    go.drugbank.com/drugs/DB12549
    Investigational

    Pyrazoloacridine has been used in trials studying the treatment of Lung Cancer, Liver Cancer, Breast Cancer, Melanoma (Skin), and Metastatic Cancer, among others.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 3-Ring
  10. Drug

    AEE-788

    go.drugbank.com/drugs/DB12558
    Investigational

    AEE788 has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.

    Categories: Heterocyclic Compounds, 2-Ring