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CHIR-124
go.drugbank.com/drugs/DB06852ExperimentalCHIR-124 is a potent inhibitor of Chk1 that potentiates the cytotoxicity of topoisomerase I poisons in vitro and in vivo.
Categories: Heterocyclic Compounds, 2-RingBMS-830216
go.drugbank.com/drugs/DB14787InvestigationalBMS-830216 is under investigation in clinical trial NCT00909766 (Safety, Pharmacokinetics and Pharmacodynamics Study to Evaluate BMS-830216 in Obese Subjects).
Cobitolimod
go.drugbank.com/drugs/DB14819InvestigationalCobitolimod is under investigation in clinical trial NCT03178669 (The Efficacy of Cobitolimod in Patients With Moderate to Severe Active Ulcerative Colitis).
Bimiralisib
go.drugbank.com/drugs/DB14846InvestigationalBimiralisib is under investigation in clinical trial NCT02723877 (PQR309 and Eribulin in Metastatic HER2 Negative and Triple-negative Breast Cancer (PIQHASSO)).
Synonyms: 2-Pyridinamine, 5-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)-4-(trifluoromethyl)-, 5-(4,6-Dimorpholino-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amineLucerastat
go.drugbank.com/drugs/DB14872InvestigationalLucerastat is under investigation in clinical trial NCT03425539 (Efficacy and Safety of Lucerastat Oral Monotherapy in Adult Subjects With Fabry Disease).
Categories: Heterocyclic Compounds, 1-RingDerazantinib
go.drugbank.com/drugs/DB14889InvestigationalDerazantinib is under investigation in clinical trial NCT03230318 (Derazantinib in Subjects With FGFR2 Gene Fusion Positive Inoperable or Advanced Intrahepatic Cholangiocarcinoma).
Categories: Heterocyclic Compounds, 2-RingTipranavir C-14
go.drugbank.com/drugs/DB15108InvestigationalTipranavir C-14 is under investigation in clinical trial NCT02253797 (Pharmacokinetics of Tipranavir/Ritonavir and Its Metabolites in Healthy Male Subjects).
Synonyms: Tipranavir C-14Categories: Heterocyclic Compounds, 1-RingGSK-239512
go.drugbank.com/drugs/DB15120InvestigationalGSK-239512 is under investigation in clinical trial NCT00474513 (An Imaging Study to Investigate the Distribution of GSK239512 in the Brain.).
Categories: Heterocyclic Compounds, 2-RingFosmanogepix
go.drugbank.com/drugs/DB15183InvestigationalFosmanogepix is under investigation in clinical trial NCT03604705 (An Efficacy and Safety Study of APX001 in Non-Neutropenic Patients With Candidemia).
Synonyms: [2-amino-3-[3-[[4-(2-pyridyloxymethyl)phenyl]methyl]isoxazol-5-yl]pyridin-1-ium-1-yl]methyl hydrogen phosphateMK-0736
go.drugbank.com/drugs/DB15209InvestigationalMK-0736 is under investigation in clinical trial NCT00679055 (A Study of How MK-0736 Affects Arterial Plaque (0736-006)(TERMINATED)).