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Caramiphen
go.drugbank.com/drugs/DB11504ExperimentalVet approvedCaramiphen is a cholinergic antagonist used in Parkinson's disease. … Additionally, it is used, in combination with [phenylpropanolamine], as a cough suppressant and nasal decongestant for the symptomatic treatment of seasonal respiratory conditions.
2-Methoxy-6-{(E)-[(4-methylphenyl)imino]methyl}phenol
go.drugbank.com/drugs/DB13869ExperimentalTIMBD is an azaresveratrol analog.
Synonyms: 2-Methoxy-6-{(E)-[(4-methylphenyl)imino]methyl}phenolRenzapride
go.drugbank.com/drugs/DB04917InvestigationalRenzapride is currently in Phase III clinical development in the United States for the treatment of constipation-predominant irritable bowel syndrome (IBS-C). … It has been suggested that renzapride is effective in the treatment of irritable bowel syndrome with alternating stool pattern. It is being developed by Alizyme of the UK.
Ginsenoside Rb1
go.drugbank.com/drugs/DB06749ExperimentalNutraceuticalGinsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant genus Panax (ginseng). … Rb1 appears to be most abundant in Panax quinquefolius (American Ginseng). Rb1 seems to affect the reproductive system in animal testicles.
Synonyms: Arasaponin E1, Panax saponin ETengonermin
go.drugbank.com/drugs/DB16689Investigational[A233270] A study also demonstrated that binding of the NGR-motif to CD13 determined both the homing of NGR-hTNF to tumor vessels and the increase in its antiangiogenic activity.[A233270] … Tengonermin, also known as NGR-hTNF, is a vascular-targeting drug.
Inactivated SARS-Cov-2 Vaccine
go.drugbank.com/drugs/DB15862InvestigationalThis strain was isolated from a patient in Wuhan, cultivated in a Vero cell line, and then subsequently inactivated using B-propiolactone. … [A220158] Currently, the vaccine is being tested in Phase 3 clinical trial in Abu Dhabi (ChiCTR2000034780).[A219758]
Palmidrol
go.drugbank.com/drugs/DB14043InvestigationalNutraceuticalA cannabinoid receptor-inactive eCB-related molecule used as prophylactic in helping to prevent respiratory viral infection. … Palmidrol is available for human use as a supplement (400 mg capsules) and as food for medical purposes In Italy and Spain (300 mg and 600 mg tablets).
Synonyms: Palmitoyl-EA, N-palmitoylethanolaminePhosphoaminophosphonic acid guanylate ester
go.drugbank.com/drugs/DB02082ExperimentalA non-hydrolyzable analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It binds tightly to G-protein in the presence of Mg2+. … The nucleotide is a potent stimulator of adenylate cyclase.
(1R,2S)-2-Phenylcyclopropanaminium
go.drugbank.com/drugs/DB02665ExperimentalA propylamine formed from the cyclization of the side chain of amphetamine. … This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders.
Zebularine
go.drugbank.com/drugs/DB03068ExperimentalAlso shown to inhibit DNA methylation and tumor growth both in vitro and in vivo. … A chemically stable, cytidine analog that displays anti-tumor properties. It acts as a transition state analog inhibitor of cytidine deaminase by binding to the active site as covalent hydrates.