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Tovorafenib
go.drugbank.com/drugs/DB15266ApprovedInvestigationalTovorafenib is a selective type II RAF kinase inhibitor with anti-tumour activity. … [A263597] It was granted accelerated approval by the FDA, making it the first FDA approval of a systemic therapy for the treatment of pediatric low-grade glioma, with BRAF rearrangements.
Gedivumab
go.drugbank.com/drugs/DB15277InvestigationalGedivumab is under investigation in clinical trial NCT01877785 (A Study of MHAA4549A to Assess Safety And Pharmacokinetics in Healthy Volunteers).
Ravoxertinib
go.drugbank.com/drugs/DB15281InvestigationalRavoxertinib is under investigation in clinical trial NCT01875705 (A Dose-Escalation Study of GDC-0994 in Patients With Locally Advanced or Metastatic Solid Tumors).
Petesicatib
go.drugbank.com/drugs/DB15297InvestigationalPetesicatib is under investigation in clinical trial NCT02295332 (A Study of RG7625 in Healthy Volunteers).
MEDI-6469
go.drugbank.com/drugs/DB15306InvestigationalMEDI-6469 is a monoclonal antibody under investigation in clinical trial NCT02205333 (A Phase 1b/2 Safety and Tolerability of MEDI6469 in Combination With Therapeutic Immune Agents or Monoclonal Antibodies
Vocimagene amiretrorepvec
go.drugbank.com/drugs/DB15331InvestigationalVocimagene amiretrorepvec is under investigation in clinical trial NCT02576665 (A Study of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Patients With Solid Tumors or Lymphoma (Toca
Dinalbuphine sebacate
go.drugbank.com/drugs/DB15341InvestigationalDinalbuphine sebacate is under investigation in clinical trial NCT02468128 (A Study of Intramuscular Sebacoyl Dinalbuphine Ester for Post-Hemorrhoidectomy Pain Management).
D-chiro-Inositol
go.drugbank.com/drugs/DB15350InvestigationalD-chiro-Inositol is under investigation in clinical trial NCT03201601 (Evaluation of the Mixture Myoinositol:D-chiro-inositol 3.6:1 in Women With Polycystic Ovary Syndrome).
Synonyms: D-Inositol, D-chiro-InositolVorsetuzumab mafodotin
go.drugbank.com/drugs/DB15352InvestigationalVorsetuzumab mafodotin is under investigation in clinical trial NCT01677390 (A Phase 1b Study of SGN-75 in Combination With Everolimus in Patients With Renal Cell Carcinoma).
Nacubactam
go.drugbank.com/drugs/DB15353InvestigationalNacubactam is under investigation in clinical trial NCT03174795 (A Study to Investigate the Pharmacokinetics of RO7079901 and Meropenem in Participants With a Complicated Urinary Tract Infection).