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Displaying results 81 - 90 of 12007 in total
  1. Drug

    Valproic acid

    go.drugbank.com/drugs/DB00313
    ApprovedInvestigational

    Valproic acid, or valproate, is an fatty acid derivative and anticonvulsant originally synthesized in 1881 by Beverly S. Burton. … [A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century.

    Synonyms: Valproic acid, 2-Propylvaleric AcidCategories: valproic acid, Fatty Acid Derivatives
  2. Drug

    Carglumic acid

    go.drugbank.com/drugs/DB06775
    ApprovedInvestigational

    Carglumic acid was approved by the U.S. Food and Drug Administration (FDA) on 18 March 2010. … Carglumic acid is a drug used for the treatment of hyperammonemia in patients with a deficiency in N-acetyl glutamate synthase.

    Synonyms: Carglumic acid, Ureidoglutaric acidCategories: Amino Acids and Derivatives, Amino Acids, Peptides, and Proteins
  3. Drug

    Tarlatamab

    go.drugbank.com/drugs/DB17256
    ApprovedInvestigational

    [L50748] It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed … across various SCLC disease stages and treatment statuses.

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsSynonyms: Immunoglobulin scfv-scfv-scfc, anti-(homo sapiens dll3 (delta-like ligand 3)) and anti-(homo sapiens cd3e (cd3 epsilon, leu-4)), monoclonal antibody single chain (scfv)2-scfc, bispecific
  4. Drug

    Mixed Carbamic Phosphoric Acid Anhydride of 7,8-Diaminononanic Acid

    go.drugbank.com/drugs/DB02927
    Experimental

    Synonyms: Mixed Carbamic Phosphoric Acid Anhydride of 7,8-Diaminononanic Acid
  5. Drug

    Mefenamic acid

    go.drugbank.com/drugs/DB00784
    Approved

    A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.

    Synonyms: Mefenamic acid, N-2,3-xylylanthranilic acidInternational brands: Ponstyl Fort
  6. Drug

    Pantothenic acid

    go.drugbank.com/drugs/DB01783
    ApprovedInvestigationalNutraceuticalVet approved

    For many animals, pantothenic acid is an essential nutrient as it is required to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats. … Pantothenic acid is the amide between pantoic acid and β-alanine and commonly found as its alcohol analog, the provitamin panthenol, and as calcium pantothenate.

    Synonyms: Pantothenic acid, D-pantothenic acidMixtures: Multivitamins and Minerals for Men, Multivitamins and Minerals for Women
  7. Drug

    Etacrynic acid

    go.drugbank.com/drugs/DB00903
    ApprovedInvestigational

    A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. … This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop or high ceiling diuretic.

    Synonyms: Etacrinic acid, Etacrynic acidCategories: etacrynic acid, Aryloxyacetic Acid Derivatives
  8. Drug

    Hyaluronic acid

    go.drugbank.com/drugs/DB08818
    ApprovedInvestigationalVet approved

    [A230133] Several preparations of hyaluronic acid have been approved by the FDA and are available in oral, topical, and injectable forms. … Karl Meyer and John Palmer obtained glycosaminoglycan (GAG) from the bovine eye, giving it the name “hyaluronic acid”.

    Synonyms: Hyaluronic acidMixtures: Hyaluronic Acid 60mg and Lidocaine 2% PF, Kaewoon for Men
  9. Drug

    Pentetic acid

    go.drugbank.com/drugs/DB14007
    ApprovedInvestigational

    Pentetic acid, also known as diethylenetriaminepentaacetic acid (DTPA), is a synthetic polyamino carboxylic acid with eight coordinate bond forming sites that can sequester metal ions and form highly stable … DTPA, along with its calcium and zinc trisodium salts, are the only FDA approved agents for the treatment of internal contamination by transuranics.

    Synonyms: Pentetic acid, Diethylene triamine pentaacetic acidCategories: Acids, Acyclic, Carboxylic Acids
  10. Drug

    Ursodeoxycholic acid

    go.drugbank.com/drugs/DB01586
    ApprovedInvestigational

    [A256272] UDCA was first approved by the FDA in 1987 for dissolution of gallstones and for primary biliary cirrhosis in 1996. … [A256267,A256463] UDCA was first characterized in the bile of the Chinese black bear and is formed by 7b-epimerization of [chenodeoxycholic acid], which is a primary bile acid.

    Categories: Bile Acids and Salts, Bile acids and derivativesSynonyms: Ursodeoxycholic acid, (3α,5β,7β)-3,7-dihydroxycholan-24-oic acid