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Dibotermin alfa
go.drugbank.com/drugs/DB11639ApprovedInvestigationalDibotermin alfa is a recombinant human bone morphogenetic protein-2 (rhBMP-2) derived from a recombinant Chinese Hamster Ovary (CHO) cell line [FDA Label]. … Dibotermin alfa was approved by the EMA in 2002 as Inductos for implantation matrix. In 2004, it was approved by the FDA and is marketed as Infuse.
Synonyms: Dibotermin alfa, Dibotermina alfaCategories: dibotermin alfaPeginterferon alfa-2b
go.drugbank.com/drugs/DB00022ApprovedInvestigationalPeginterferon alfa-2b is derived from the alfa-2b moeity of recombinant human interferon and acts by binding to human type 1 interferon receptors. … The use of Peginterferon alfa-2b has largely declined since newer interferon-free antiviral therapies have been developed.
Synonyms: Peg interferon alfa-2b, Peginterferon alfa-2bCategories: Alfa Interferons, peginterferon alfa-2bAntithrombin Alfa
go.drugbank.com/drugs/DB11166ApprovedAntithrombin Alfa is a recombinant antithrombin , an anticoagulant, that is used for the prevention of thromboembolic events in patients that have hereditary deficiency of antithrombin in high risk situations
Synonyms: Antithrombin AlfaChoriogonadotropin alfa
go.drugbank.com/drugs/DB00097ApprovedInvestigationalRecombinant human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ASN-30, SER-121, SER-127, SER-1...
Categories: choriogonadotropin alfaSynonyms: Choriogonadotropin alfaDrotrecogin alfa
go.drugbank.com/drugs/DB00055ApprovedWithdrawnDrotrecogin alfa is activated human protein C that is synthesized by recombinant DNA technology. … Drotrecogin alfa was withdrawn from the market after a major study indicated that it was not effective in improving outcomes in patients with sepsis.
Categories: drotrecogin alfa (activated)Synonyms: Drotrecogin-alfa, Drotrecogin alfa activatedEfmoroctocog alfa
go.drugbank.com/drugs/DB11607ApprovedInvestigationalEfmoroctocog alfa is a fully recombinant factor VIII-Fc fusion protein (rFVIIIFc) with an extended half-life compared with conventional factor VIII (FVIII) preparations, including recombinant FVIII (rFVIII … In animal models of haemophilia, efmoroctocog alfa demonstrated an approximately two-fold longer t½ than commercially available rFVIII products [A31551].
Synonyms: Efmoroctocog alfaEftrenonacog alfa
go.drugbank.com/drugs/DB11608ApprovedEftrenonacog alfa is a long-acting recombinant fusion protein used in the treatment of hemophilia B. … Eftrenonacog alfa acts as a replacement therapy to restore the levels of factor IX and allow normal hemostasis.
Synonyms: Eftrenonacog alfaCuprous chloride
go.drugbank.com/drugs/DB15535InvestigationalSynonyms: Copper monochloride, Copper(1+) chloride