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Tolterodine
go.drugbank.com/drugs/DB01036ApprovedInvestigationalTolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.
Products: Mylan-tolterodine ER, TOLTERODIN HEXAL RET 4 MGNilvadipine
go.drugbank.com/drugs/DB06712ApprovedNilvadipine is a calcium channel blocker (CCB) for the treatment of hypertension.
Products: ESCOR 8MG RETARDKAPSELN, Tensan retard 8 mg - KapselnIxazomib
go.drugbank.com/drugs/DB09570ApprovedInvestigationalBecause it is a modified peptide boronic acid with one chiral center,[A264329] it is considered a boronate proteasome inhibitor.[A7948] More than 99% of the drug compound is the R-enantiomer. … [A264319] It was later approved by Health Canada on August 3, 2016,[L51239] and by the EMA on November 21, 2016.
Products: NINLARO CAPSULE 4mg, Ninlaro Hard Capsule 4mgDextrothyroxine
go.drugbank.com/drugs/DB00509ApprovedWithdrawnThe major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (monoiodotyrosine) and the coupling of iodotyrosines (diiodotyrosine) in the thyroglobulin. Thyroxine is released from thyroglobul...
Products: Choloxin Tablet 4mg, Choloxin - Tab 4mgPravastatin
go.drugbank.com/drugs/DB00175ApprovedInvestigationalIt was the first statin administered as the active form and not as a prodrug.[T274] This drug was developed by Sankyo Co.
Mixtures: PRAVAFEN HARD CAPSULES 40mg/160mg, Pravafen 40mg/160mg Hard CapsulesProducts: PRAVASTATINA EG, PRAVASTATIN HEU 40MG NETHydrochlorothiazide
go.drugbank.com/drugs/DB00999ApprovedInvestigationalVet approved[A185138] It is indicated to treat edema and hypertension.[A185138,L8447,L8450] Hydrochlorothiazide use is common but declining in favour of angiotensin converting enzyme inhibitors.
Mixtures: CANDECOR COMP 8MG/12.5MG, CANDECOR COMP 8MG/12.5MGProducts: HCT - CT 12.5 MG TABLETTEN, BENAZEPRIL IDROCLOROTIAZIDE EGIsosorbide mononitrate
go.drugbank.com/drugs/DB01020ApprovedInvestigationalIt is an anti-anginal agent that works by relaxing the smooth muscles of both arteries and veins, but but predominantly veins to reduce cardiac preload. … [L11698] It is available in oral tablets generically and under the brand name ISMO and Monoket. The extended-release forms of the drug are also available generically and under the brand name Imdur.
Products: IS 5 MONO RATIO 40MG RET, ISMN - CT 40MG TABLETTENBrexpiprazole
go.drugbank.com/drugs/DB09128ApprovedInvestigationalIt also displays stronger antagonism at the 5-HT1A and 5-HT2A receptors.[A182186, A38385, A259661] Brexpiprazole was first approved by the FDA on July 10, 2015. … It has a high affinity for serotonin, dopamine and alpha (α)-adrenergic receptors.
Products: REXULTI FILM-COATED TABLETS 4MG, Rexulti 4mg film-coated tabletsMethylphenidate
go.drugbank.com/drugs/DB00422ApprovedInvestigationalAlso known as the marketed products Ritalin, Concerta, or Biphentin, methylphenidate is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve the … system allows for a sustained effect for 10-12 hours, allowing for once-daily dosing that covers the major times that ADHD impairment might occur (such as school, homework periods, during the work day, etc
Products: Methylin ER, Metadate ERRisperidone
go.drugbank.com/drugs/DB00734ApprovedInvestigational[L12885] It is one of the most widely used SGAs. [Paliperidone], another commonly used SGA, is the primary active metabolite of risperidone (i.e. 9-hydroxyrisperidone). … [L12885] Risperidone binds with a very high affinity to 5-HT2A receptors, approximately 10-20 fold greater than the drug's binding affinity to D2 receptors, and carries lesser activity at several off-targets
Products: RISPERIDON HEU 4MG NET, RISPERIDON STADA 8MG