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Displaying results 81 - 90 of 9725 in total
  1. Drug

    Perphenazine

    go.drugbank.com/drugs/DB00850
    ApprovedInvestigational

    An antipsychotic phenothiazine derivative with actions and uses similar to those of chlorpromazine.

    Mixtures: PMS-levazine 3/15 Tab, PMS-levazine 2/25 TabProducts: PMS Perphenazine Tab 16mg, Trilafon Conc 16mg/5ml
  2. Drug

    Doxorubicin

    go.drugbank.com/drugs/DB00997
    ApprovedInvestigational

    [A257709] Although its detailed molecular mechanisms have yet to be understood, doxorubicin is generally thought to exert its effect through DNA intercalation, which eventually leads to DNA damage and … [A257614] Thanks to its efficacy and broad effect, doxorubicin was approved by the FDA in 1974 to treat a variety of cancer, including but not limited to breast, lung, gastric, ovarian, thyroid, non-Hodgkin

    Products: ADRIMEDAC 10MG (2MG/ML), DOXORUBICIN AU 2MG/ML 10MG
  3. Drug

    Escitalopram

    go.drugbank.com/drugs/DB01175
    ApprovedInvestigational

    [A185420] It is used to restore serotonergic function in the treatment of depression and anxiety. … the vast majority of citalopram’s clinical activity, with some evidence suggesting that the R-enantiomer of racemic citalopram actively dampens the activity of escitalopram rather than existing simply as

    Products: ESCITALOPRAM 20MG/ML NET, PMS-escitalopram
  4. Drug

    Oxtriphylline

    go.drugbank.com/drugs/DB01303
    Approved

    It is marketed under the name Choledyl SA, and several forms of oxytriphylline have been discontinued. In the US, oxtriphylline is no longer available. … As such, oxytriphylline is indicated mainly for asthma, bronchospasm, and COPD (i.e. all the same indications as the other theophyllines).

    Mixtures: PMS-oxtriphylline ElixirProducts: PMS Oxtriphylline Syr Pediatric 10mg/ml, Rouphylline Syr 10mg/ml
  5. Drug

    Panobinostat

    go.drugbank.com/drugs/DB06603
    ApprovedInvestigational

    Panobinostat acts as a non-selective histone deacetylase inhibitor (pan-HDAC inhibitor) and it is the most potent DAC inhibiting agent available on the market. … The approval was accelerated based on progression-free survival, therefore confirmatory trials by the sponsor to demonstrate clinical efficacy in multiple myeloma treatment are in progress of being conducted

    Products: FARYDAK HARD GELATIN CAPSULE 10mg, FARYDAK HARD GELATIN CAPSULE 15mg
  6. Drug

    Phenobarbital

    go.drugbank.com/drugs/DB01174
    ApprovedInvestigational

    A barbituric acid derivative that acts as a nonselective central nervous system depressant. … It promotes binding to inhibitory gamma-aminobutyric acid subtype receptors, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.

    Mixtures: Dilantin W Phenobarbital 15mg, Dilantin W Phenobarbital 30mg CapProducts: Phenobarbital Tab 15mg, Phenobarbital Tablet 15mg
  7. Drug

    Telmisartan

    go.drugbank.com/drugs/DB00966
    ApprovedInvestigational

    Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular

    Mixtures: TWYNSTA 40MG/10MG, TWYNSTA 40MG/10MGProducts: TELMISARTAN HEU 20MG NET, TELMISARTAN HEU 40MG NET
  8. Drug

    Pregabalin

    go.drugbank.com/drugs/DB00230
    ApprovedInvestigational

    [L1006,L7066] It may have dependence liability if misused but the risk appears to be highest in patients with current or past substance use disorders.[A31161] … [A173995] It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other conditions.

    Mixtures: BEGOLIN PLUS 75MG/1MG FILM TABLET, 14 ADET, BEGOLIN PLUS 150MG/1MG FILM TABLET, 56 ADETProducts: PMS-pregabalin, PREGABALIN EG
  9. Drug

    Pimozide

    go.drugbank.com/drugs/DB01100
    Approved

    A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to haloperidol for the suppression of vocal and motor tics in patients with Tourette syndrome. … Although the precise mechanism of action is unknown, blockade of postsynaptic dopamine receptors has been postulated. (From AMA Drug Evaluations Annual, 1994, p403)

    Products: Orap Tab 10mg, ORAP 1MG
  10. Drug

    Ropinirole

    go.drugbank.com/drugs/DB00268
    ApprovedInvestigational

    In 2005, it was the first drug approved in the US for the management of primary moderate to severe restless legs syndrome [A174547]. … It is manufactured by GlaxoSmithKline Pharmaceuticals. Ropinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease.

    Products: PMS-ropinirole, REQUIP 1MG