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Displaying results 81 - 90 of 224 in total
  1. Pathway

    Dexchlorpheniramine maleate H1 Antihistamine Smooth Muscle Relaxation Action Pathway

    smpdb.ca/view/SMP0174954
    Drug action

    Dexchlorpheniramine maleate also inhibits the H1 histamine receptor on bronchiole smooth muscle myocytes. … Dexchlorpheniramine maleate is a first generation H1-antihistamine used to treat allergic and vasomotor rhinitis, allergic conjunctivitis, and mild urticaria and angioedema.

    Drugs: Calcium · Magnesium cation · Dexchlorpheniramine maleate
  2. Target

    Malto-oligosyltrehalose trehalohydrolase

    go.drugbank.com/bio_entities/BE0002951
    TargetDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)

    Polypeptides: Malto-oligosyltrehalose trehalohydrolase
  3. Drug

    Betahistine

    go.drugbank.com/drugs/DB06698
    ApprovedInvestigational

    Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. It has a significant impact on both the physical and social functioning of affected individuals. Betahistine is a histamine...

    Salts: Betahistine maleate
  4. Target

    Succinate dehydrogenase cytochrome b560 subunit, mitochondrial

    go.drugbank.com/bio_entities/BE0002257
    TargetEnzymeHumans

    SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate (By similarity).

    Synonyms: Malate dehydrogenase [quinone] cytochrome b560 subunit
  5. Drug

    Reveglucosidase alfa

    go.drugbank.com/drugs/DB17665
    Investigational

    Synonyms: Des-(2-7)-human insulin-like growth factor ii fusion protein with glycyl-l-alanyl-l-prolyl-human lysosomal alpha-glucosidase (acid maltase, aglucosidase alfa) produced in chinese hamster ovary (cho) cells
  6. Drug

    Edonerpic

    go.drugbank.com/drugs/DB05938
    Investigational

    Edonerpic is a neurotrophic agent intended for the treatment of Alzheimer's disease which is under phase I clinical trial.

    Salts: Edonerpic maleate
  7. Drug

    Cediranib

    go.drugbank.com/drugs/DB04849
    Investigational

    The novel indole-ether quinazoline Cediranib is a highly potent (IC50 < 1 nmol/L) ATP-competitive inhibitor of recombinant KDR tyrosine kinase in vitro. It is being developed clinically as a once-daily oral therapy for the treatment o...

    Salts: Cediranib maleate
  8. Drug

    Setiptiline

    go.drugbank.com/drugs/DB09304
    Experimental

    Setiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). In Japan, the company Mochida started its commercialization for the treatment of depression started in 1989.

    Salts: Setiptiline maleate
  9. Drug

    Aptazapine

    go.drugbank.com/drugs/DB09305
    Experimental

    Aptazapine (CGS-7525A) was a tetracyclic antidepressant developed in the 1980s. Aptazapine had noradrenergic and specific serotonergic activity. It antagonised α2 adrenergic receptors approximately 10 times more effectively than mianseri...

    Salts: Aptazapine maleate
  10. Drug

    Cinepazide

    go.drugbank.com/drugs/DB12123
    Investigational

    Cinepazide has been used in trials studying the treatment of Ischemic Stroke.

    Salts: Cinepazide Maleate