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Peanut oil
go.drugbank.com/drugs/DB13964ApprovedWithdrawn[A33169] Under the FDA, peanut oil is categorized as an approved inactive ingredient for its use in drug products. … [L2242] Under Health Canada, it is approved as an active ingredient in over-the-counter combination products.[L1113]
Estriol
go.drugbank.com/drugs/DB04573ApprovedInvestigationalVet approvedA hydroxylated metabolite of estradiol or estrone that has a hydroxyl group at C3-beta, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen. … Though estriol is used as part of the primarily North American phenomenon of bioidentical hormone replacement therapy, it is not approved for use by the FDA or Health Canada.
Categories: P-glycoprotein inducers, P-glycoprotein substratesPotassium hydroxide
go.drugbank.com/drugs/DB11153ApprovedPotassium hydroxide is also a precursor to other potassium compounds. Potassium hydroxide is used in food to adjust pH, as a stabilizer, and as a thickening agent. … Potassium hydroxide, also known as _lye_ is an inorganic compound with the chemical formula _KOH_.
Categories: Compounds used in a research, industrial, or household settingAnileridine
go.drugbank.com/drugs/DB00913ApprovedIllicitWithdrawnAnileridine is a synthetic opioid and strong analgesic medication. It is a narcotic pain reliever used to treat moderate to severe pain.
Synonyms: N-β-(p-aminophenyl)ethylnormeperidine, ethyl 1-(p-aminophenethyl)-4-phenylisonipecotateRiociguat
go.drugbank.com/drugs/DB08931ApprovedInvestigationalRiociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for … the treatment of patients with inoperable CTEPH (chronic thromboembolic pulmonary hypertension), or persistent/recurrent PH (pulmonary hypertension) after pulmonary endarterectomy in WHO FC II or III.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesLevopropoxyphene
go.drugbank.com/drugs/DB06793ApprovedWithdrawnLevopropoxyphene is a stereoisomer of propoxyphene in the form of 2S, 3R enantiomer. It was sold as an antitussive, but it was removed from the market in the 70s. … This drug presented different dosages and it was administered as a capsule or suspension.
Topotecan
go.drugbank.com/drugs/DB01030ApprovedInvestigationalAn antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, MATE 1 Substrates with a Narrow Therapeutic IndexProducts: TOPOXIN 4 MG IV INF.ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET, HYCAMTIN IV LİYOFİLİZE TOZ İÇEREN ENJEKTABL FLAKON, 1 ADETMequinol
go.drugbank.com/drugs/DB09516ApprovedWithdrawnIt is used as an inhibitor for acrylic monomers and acrylonitirles, as a stabilizer for chlorinated hydrocarbons and ethyl cellulose, as an ultraviolet inhibitor, as a chemical intermediate in the manufacture … Mequinol is a phenol used in various applications.
Categories: Compounds used in a research, industrial, or household settingDimethicone 410
go.drugbank.com/drugs/DB14005ApprovedDimethicone is a silicone-based polymer used as a moisturizer in different skin OTC products.[A32462] It is formed by repeated polymeric units of -(CH3)2SiO- with a terminal trimethyl siloxy unit. … [L1769] It is currently recognized by the FDA as a skin protectant OTC ingredient for human use in a concentration of 1-30%.
Sulfamerazine
go.drugbank.com/drugs/DB01581ApprovedVet approvedWithdrawnA sulfanilamide that is used as an antibacterial agent.
Synonyms: (p-Aminobenzolsulfonyl)-2-amino-4-methylpyrimidin, 2-(p-Aminobenzolsulfonamido)-4-methylpyrimidine