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Multipotent adult arogenitor cells
go.drugbank.com/drugs/DB15742InvestigationalAfter administration, the cells are cleared from the body over time. Currently, MultiStem is being investigated against neurological, inflammatory, immune, and cardiovascular diseases and conditions.
ATX-101
go.drugbank.com/drugs/DB05780InvestigationalATX-101 demonstrates a relative selectivity for fat over other tissues.
CYP-001
go.drugbank.com/drugs/DB15739InvestigationalThese cells have advantage over other MSCs because a large amount can be obtained from a single healthy blood donor, negating the risks from donor-and expansion dependent variability.
IMM101
go.drugbank.com/drugs/DB15851ExperimentalAs of July 2020, researchers from the Ottawa Hospital and Queen’s University, in partnership with the Canadian Cancer Society-funded Canadian Cancer Trials Group (CCTG), are conducting a trial in over
Protamine sulfate
go.drugbank.com/drugs/DB09141ApprovedInvestigationalformal introduction via US FDA approval in 1939, protamine sulfate has occupied an important therapeutic niche as perhaps the only viable option for reversing the anticoagulant effect of heparin use for over
Votucalis
go.drugbank.com/drugs/DB05032InvestigationalrEV131 is in development for allergic rhinitis, asthma and several inflammatory eye diseases. It is a topically delivered small protein that acts as an anti-inflammatory agent.
Human cord blood hematopoietic progenitor cell
go.drugbank.com/drugs/DB11054ApprovedThe unrelated donor transplant setting has several advantages over related donor transplant and bone marrow transplantation; it allows shorter time to transplant and tolerance of 1–2 human leukocyte antigen
Bevacizumab
go.drugbank.com/drugs/DB00112ApprovedInvestigational[L45793,L43130] For over a decade, bevacizumab was also used off-label by intravitreal injection to treat neovascular (wet) age-related macular degeneration and other retinal conditions, repackaged from
Categories: VEGF/VEGFR (Vascular Endothelial Growth Factor / -Receptor) inhibitorsEtrolizumab
go.drugbank.com/drugs/DB12189Investigational[A244564, A244569, A244579, A244584] A recent class of drugs designed to impair lymphocyte homing, so-called "anti-trafficking agents" (ATAs), have shown some success and include approved drugs such as
Categories: Integrin Receptor AntagonistPravastatin
go.drugbank.com/drugs/DB00175ApprovedInvestigationalPravastatin is the 6-alpha-hydroxy acid form of mevastatin. Pravastatin was firstly approved in 1991 becoming the second available statin in the United States. It was the first statin administered as the active form and not as a prodrug....