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Displaying results 1 - 10 of 1717 in total
  1. Drug

    Bupropion

    go.drugbank.com/drugs/DB01156
    ApprovedInvestigational

    [L6562] Studies have shown that the combined activity of bupropion and [naltrexone] increase the firing rate of hypothalamic pro-opiomelanocortin (POMC) neurons and blockade of opioid receptor-mediated … More specifically, bupropion binds to the norepinephrine transporter (NET) and the dopamine transporter (DAT).

    Synonyms: BupropionSalts: Bupropion hydrobromide, Bupropion hydrochloride
  2. Drug

    Obexelimab

    go.drugbank.com/drugs/DB15032
    Investigational

    Obexelimab is under investigation in clinical trial NCT02725515 (A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus).

    Synonyms: XMAB5871 (HUMANIZED ANTI-CD19 ANTIBODY WITH AN FC PORTION ENGINEERED FOR INCREASED AFFINITY (200- TO 400-FOLD OVER NATIVE IGG) TO FCGRIIB)
  3. Pathway

    Bupropion Metabolism

    smpdb.ca/view/SMP0125320
    Metabolic

    Bupropion is an anti-depressant and smoking cessation drug taken orally. … Bupropion is not transported by any major hepatic transporters.

    Drugs: Bupropion · Mesoheme
  4. Pathway

    Bupropion Action Pathway

    smpdb.ca/view/SMP0125268
    Drug action

    Dopamine is released into the synapse where it is much more difficult for it to re-enter the presynaptic neuron due to bupropion inhibiting the sodium-dependent dopamine receptor. … Bupropion does this at least for alpha-1A adregnergic receptors in the limbic system.

    Drugs: Pyridoxal phosphate · Ascorbic acid · Tyrosine · ATP · Norepinephrine · Dopamine +8 more
    Enzymes: D(1A) dopamine receptor, Alpha-1A adrenergic receptor
  5. Drug

    Rice bran oil

    go.drugbank.com/drugs/DB11293
    ApprovedInvestigational

    Rice bran oil is extracted from the hard outer brown layer of rice after chaff (rice husk) used for high-temperature cooking methods such as deep frying and stir frying. It contains monosaturated fatty acids, polyunsaturated fatty acids,...

    Products: Claritying turn over rice perfect oil foam cleanser
  6. Drug

    Avobenzone

    go.drugbank.com/drugs/DB09495
    ApprovedInvestigational

    Avobenzone has the ability to absorb ultraviolet light over wider range of wavelengths. It is included in many commercially available sunscreens which are used as wide spectrum sunscreens.

    Mixtures: Bobbi Brown All Over Bronzing Gel SPF 15, Exuviance Optilight All-Over Dark Spot Minimizer SPF 25Products: Leaders Sunbuddy All Over Sun
  7. Drug

    Antithrombin III human

    go.drugbank.com/drugs/DB11598
    ApprovedInvestigational

    A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.

    Products: . - Pulver und Lösungsmittel zur Herstellung einer Injektions- oder Infusionslösung, Pulver und Lösungsmittel zur Herstellung einer Injektions- oder Infusionslösung
  8. Drug

    Teicoplanin

    go.drugbank.com/drugs/DB06149
    ApprovedInvestigationalWithdrawn

    Teicoplanin is a glycopeptide antibiotic consisting of a mixture of several compounds, five major (named teicoplanin A2-1 through A2-5) and four minor (named teicoplanin RS-1 through RS-4). All teicoplanins share a same glycopeptide core...

    Products: Teicoplanin Mylan 100 mg Pulver zur Herstellung einer Injektions-/Infusionslösung oder einer Lösung zum Einnehmen, Teicoplanin Mylan 200 mg Pulver zur Herstellung einer Injektions-/Infusionslösung oder einer Lösung zum Einnehmen
  9. Drug

    Mitomycin

    go.drugbank.com/drugs/DB00305
    ApprovedInvestigational

    [A193419] Mitomycin's cross-linking activity has resulted in its approval for the treatment of a variety of cancers - the most recent of which is an April 2020 approval for its use in low-grade Upper

    Products: Mitomycin Accord 10 mg Pulver zur Herstellung einer Injektions- / Infusionslösung oder Lösung zur intravesikalen Anwendung, Mitomycin Accord 2 mg Pulver zur Herstellung einer Injektions- / Infusionslösung oder Lösung zur intravesikalen Anwendung
  10. Drug

    Conestat alfa

    go.drugbank.com/drugs/DB09228
    Approved

    C1 Esterase Inhibitor (Recombinant) is a recombinant analogue of endogenous complement component-1 esterase inhibitor (rhC1INH), purified from the milk of transgenic rabbits. The primary function of endogenous C1INH is to regulate the ac...

    Products: Pulver und Lösungsmittel zur Herstellung einer Injektions- oder Infusionslösung