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Displaying results 891 - 900 of 10000 in total
  1. Drug

    Bortezomib

    go.drugbank.com/drugs/DB00188
    ApprovedInvestigational

    Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma and mantle cell lymphoma. … [A204083] The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexSynonyms: [(1R)-3-methyl-1-({(2S)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acid, N-[(1R)-1-(DIHYDROXYBORYL)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide
  2. Drug

    Rumex crispus whole

    go.drugbank.com/drugs/DB14267
    Approved

    Rumex crispus whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Products: JEUNCELL a drug for atopic dermatitis
  3. Drug

    Horseradish

    go.drugbank.com/drugs/DB10674
    Approved

    Horseradish allergenic extract is used in allergenic testing.

    Products: Nwk A-FV
  4. Drug

    Dimenhydrinate

    go.drugbank.com/drugs/DB00985
    ApprovedInvestigational

    [L32980,L32985,L32995] Dimenhydrinate is a combination of [Diphenhydramine] and [8-chlorotheophylline] in a salt form, with 53%-55.5% dried diphenhydramine, and 44%-47% died 8-chlorotheophylline. … [A1539] Dimenhydrinate was granted FDA approval on 31 May 1972.[L32975]

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 8-chloro-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1), N,N-dimethyl-2-diphenylmethoxyethylamine 8-chlorotheophyllinate
  5. Drug

    Iron

    go.drugbank.com/drugs/DB01592
    ApprovedInvestigational

    A metallic element found in certain minerals, in nearly all soils, and in mineral waters. It is an essential constituent of hemoglobin, cytochrome, and other components of respiratory enzyme systems.

    Mixtures: Nephron FA, Nephron FAProducts: Fera Liq 16.7mg/15ml, COMPLEJO DE HIDROXIDO DE HIERRO EN SACAROSA EQUIVALENTE A 100 MG DE HIERRO ELEMENTAL INYECTABLE
  6. Drug

    Lipoic acid

    go.drugbank.com/drugs/DB00166
    ApprovedInvestigationalNutraceutical

    A vitamin-like antioxidant.

    Mixtures: Protect Cardio AF, Live-well™ MITOcare™ Liqfil™ Vegetable CapsuleCategories: Compounds used in a research, industrial, or household setting, Vitamin B Complex
  7. Drug

    Hydrogen peroxide

    go.drugbank.com/drugs/DB11091
    ApprovedInvestigationalVet approved

    Hydrogen peroxide is also considered as a generally recognized as safe compound by the FDA [L2024]; it is used as an antimicrobial agent in starch and cheese products, and as an oxidizing and reducing … Hydrogen peroxide is an unstable compound in the presence of a base or catalyst, and is typically stored with a stabilizer in a weakly acidic solution.

    Mixtures: Defense AG Disinfectant, Defense AG DisinfectantCategories: Compounds used in a research, industrial, or household setting
  8. Target

    Nuclear receptor subfamily 4 group A member 3

    go.drugbank.com/bio_entities/BE0008998
    TargetHumans

    During inner ear, plays a role as a key mediator of the proliferative growth phase of semicircular canal development (By similarity). … In mast cells activated by Fc-epsilon receptor cross-linking, promotes the synthesis and release of cytokines but impairs events leading to degranulation (By similarity).

    Polypeptides: Nuclear receptor subfamily 4 group A member 3Synonyms: Nuclear hormone receptor NOR-1, Neuron-derived orphan receptor 1
  9. Target

    Leukocyte immunoglobulin-like receptor subfamily A member 4

    go.drugbank.com/bio_entities/BE0013620
    TargetHumans

    production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides, indicating it functions as a … Activates a signaling cascade in complex with FCER1G that results in phosphorylation of Src family and Syk kinases and thereby triggers mobilization of intracellular Ca(2+) (PubMed:16735691, PubMed:19564354

    Polypeptides: Leukocyte immunoglobulin-like receptor subfamily A member 4
  10. Drug

    Angelica archangelica root

    go.drugbank.com/drugs/DB14283
    Approved

    Angelica archangelica root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Products: Park no suk a clear walk of park