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Displaying results 9001 - 9010 of 10000 in total
  1. Drug

    Pimicotinib

    go.drugbank.com/drugs/DB18972
    Investigational

    Pimicotinib is under investigation in clinical trial NCT05804045 (Study of Pimicotinib (ABSK021) for Tenosynovial Giant Cell Tumor (MANEUVER)).

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-Pyrrolidinecarboxamide, 3,3-dimethyl-N-[6-methyl-5-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]-2-pyridinyl]-2-oxo-, 3,3-Dimethyl-N-[6-methyl-5-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]-2-pyridinyl]-2-oxo-1-pyrrolidinecarboxamide
  2. Drug

    Baxdrostat

    go.drugbank.com/drugs/DB19090
    ApprovedInvestigational

    On May 18, 2026, baxdrostat was approved by the FDA as a first-in-class aldosterone synthase inhibitor for the treatment of hypertension in combination with other antihypertensive drugs [L56189]. … It targets aldosterone excess, a primary underlying driver of treatment resistance and organ damage in cardiovascular diseases [A275512, A275515].

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: (+)-(r)-n-(4-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-5,6,7,8-tetrahydroisoquinolin-8-yl)propionamide, N-((8r)-5,6,7,8-tetrahydro-4-(1,2,3,4-tetrahydro-1-methyl-2-oxo-6-quinolinyl)-8-isoquinolinyl)propanamide
  3. Drug

    Isuzinaxib

    go.drugbank.com/drugs/DB19109
    Investigational

    Isuzinaxib is under investigation in clinical trial NCT05758896 (Study of APX-115 in Contrast Induced Acute Kidney Injury in Subjects Undergoing PCI).

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-(pyridin-2-yl)-3-phenyl-4-propyl-1h-pyrazol-5-ol, 1h-pyrazol-5-ol, 3-phenyl-4-propyl-1-(2-pyridinyl)-
  4. Drug

    Coptisine

    go.drugbank.com/drugs/DB19308
    Experimental

    Synonyms: 6,7-dihydrobis(1,3)benzodioxolo(5,6-a:4',5'-g)quinolizinium, Bis(1,3)benzodioxolo(5,6-a:4',5'-g)quinolizinium, 6,7-dihydro-Categories: Heterocyclic Compounds with 4 or More Rings
  5. Drug

    Farglitazar

    go.drugbank.com/drugs/DB19311
    Investigational

    Synonyms: L-TYROSINE, N-(2-BENZOYLPHENYL)-O-(2-(5-METHYL-2-PHENYL-4-OXAZOLYL)ETHYL)-, N-(O-BENZOYLPHENYL)-O-(2-(5-METHYL-2-PHENYL-4-OXAZOLYL)ETHYL)-L-TYROSINECategories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Zelquistinel

    go.drugbank.com/drugs/DB19336
    Investigational

    Zelquistinel is under investigation in clinical trial NCT06547489 (GATE-251 or Placebo for the Reduction of Symptoms of Major Depressive Disorder).

    Synonyms: tert-butyl (4S)-2-[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]-3-oxo-2,5-diazaspiro[3.4]octane-5-carboxylate
  7. Drug

    Mitomycin A

    go.drugbank.com/drugs/DB19369
    Experimental

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: 6-methoxy analog of mitomycin c, Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 8-(((aminocarbonyl)oxy)methyl)-1,1a,2,8,8a,8b-hexahydro-6,8a-dimethoxy-5-methyl-, (1as,8s,8ar,8bs)-
  8. Drug

    NITHIAMIDE

    go.drugbank.com/drugs/DB19371
    ApprovedWithdrawn

    Synonyms: Acetamide, n-(5-nitro-2-thiazolyl)-, N-(5-nitro-2-thiazolyl)acetamideCategories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Zoxazolamine

    go.drugbank.com/drugs/DB19372
    ApprovedWithdrawn

    Synonyms: 2-amino-5-chlorobenzoxazole, 5-chloro-2-benzoxazolamineCategories: Heterocyclic Compounds, 2-Ring
  10. Drug

    Syrosingopine

    go.drugbank.com/drugs/DB19379
    ApprovedWithdrawn

    Synonyms: -dimethoxy-3.beta.,20.alpha.-yohimban-16.beta.-carboxylate 4-hydroxy, Yohimban-16-carboxylic acid, 18-((4-((ethoxycarbonyl)oxy)-3,5-dimethoxybenzoyl)oxy)-11,17-dimethoxy-, methyl ester, (3.beta.,16.beta.,17.alpha.,18.beta.,20.alpha.)-Categories: Heterocyclic Compounds, 2-Ring