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Displaying results 9011 - 9020 of 10000 in total
  1. Target

    Neuronal acetylcholine receptor subunit alpha-4

    go.drugbank.com/bio_entities/BE0000849
    TargetHumans

    Found in two major stoichiometric forms,(CHRNA4)3:(CHRNB2)2 and (CHRNA4)2:(CHRNB2)3, the two stoichiometric forms differ in their unitary conductance, calcium permeability, ACh sensitivity and potentiation

    Polypeptides: Neuronal acetylcholine receptor subunit alpha-4
  2. Target

    Cytochrome b6-f complex subunit 4

    go.drugbank.com/bio_entities/BE0002473
    TargetMastigocladus laminosus

    Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.

    Polypeptides: Cytochrome b6-f complex subunit 4
  3. Target

    Sodium channel regulatory subunit beta-4

    go.drugbank.com/bio_entities/BE0003638
    TargetHumans

    Regulatory subunit of multiple voltage-gated sodium (Nav) channels directly mediating the depolarization of excitable membranes. Navs, also called VGSCs (voltage-gated sodium channels) or VDSCs (voltage-dependent sodium channels), operat...

    Polypeptides: Sodium channel regulatory subunit beta-4
  4. Target

    Receptor tyrosine-protein kinase erbB-4

    go.drugbank.com/bio_entities/BE0004772
    TargetHumans

    Isoform JM-A CYT-2 and isoform JM-B CYT-2 lack the phosphotyrosine that mediates interaction with PIK3R1, and hence do not phosphorylate PIK3R1, do not protect cells against apoptosis, and do not promote … Isoform JM-A CYT-1 and isoform JM-B CYT-1 phosphorylate PIK3R1, leading to the activation of phosphatidylinositol 3-kinase and AKT1 and protect cells against apoptosis.

    Polypeptides: Receptor tyrosine-protein kinase erbB-4Synonyms: Proto-oncogene-like protein c-ErbB-4
  5. Target

    Heat shock 70 kDa protein 4

    go.drugbank.com/bio_entities/BE0009027
    TargetHumans

    Polypeptides: Heat shock 70 kDa protein 4Synonyms: Heat shock 70-related protein APG-2, Heat shock protein family H member 2
  6. Target

    MAP/microtubule affinity-regulating kinase 4

    go.drugbank.com/bio_entities/BE0009482
    TargetHumans

    Serine/threonine-protein kinase (PubMed:14594945, PubMed:15009667, PubMed:23184942, PubMed:23666762). Phosphorylates the microtubule-associated protein MAPT/TAU (PubMed:14594945, PubMed:23666762). Also phosphorylates the microtubule-asso...

    Polypeptides: MAP/microtubule affinity-regulating kinase 4
  7. Target

    Inositol polyphosphate 4-phosphatase type II

    go.drugbank.com/bio_entities/BE0011457
    EnzymeHumans

    Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate and inositol 3,4-trisphosphate (PubMed:24070612, PubMed:24591580).

    Polypeptides: Inositol polyphosphate 4-phosphatase type IISynonyms: Type II inositol 3,4-bisphosphate 4-phosphatase
  8. Pathway

    Cardiolipin Biosynthesis CL(20:3(11Z,14Z,17Z)/18:4(6Z,9Z,12Z,15Z)/18:4(6Z,9Z,12Z,15Z)/20:4(5Z,8Z,11Z,14Z))

    smpdb.ca/view/SMP0244166
    Metabolic

    Third, the enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2-diacyl-sn-glycerol 3-phosphate) by esterifying an acyl-group to the sn-2 position of the … Fifth, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase synthesizes phosphatidylglycerophosphate (PGP).

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
    Enzymes: Phosphatidate cytidylyltransferase 2, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial
  9. Pathway

    Cardiolipin Biosynthesis CL(20:3(11Z,14Z,17Z)/18:4(6Z,9Z,12Z,15Z)/20:4(5Z,8Z,11Z,14Z)/18:4(6Z,9Z,12Z,15Z))

    smpdb.ca/view/SMP0244204
    Metabolic

    Third, the enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2-diacyl-sn-glycerol 3-phosphate) by esterifying an acyl-group to the sn-2 position of the … Fifth, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase synthesizes phosphatidylglycerophosphate (PGP).

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
    Enzymes: Phosphatidate cytidylyltransferase 2, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial
  10. Pathway

    Cardiolipin Biosynthesis CL(20:4(5Z,8Z,11Z,14Z)/18:4(6Z,9Z,12Z,15Z)/18:4(6Z,9Z,12Z,15Z)/20:3(11Z,14Z,17Z))

    smpdb.ca/view/SMP0244351
    Metabolic

    Third, the enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2-diacyl-sn-glycerol 3-phosphate) by esterifying an acyl-group to the sn-2 position of the … Fifth, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase synthesizes phosphatidylglycerophosphate (PGP).

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
    Enzymes: Phosphatidate cytidylyltransferase 2, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial