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Gemogenovatucel-T
go.drugbank.com/drugs/DB17412InvestigationalFurin is a convertase involved in the activation of TGFβ-1 and TGFβ-2.[A255163] Gemogenovatucel-T is being investigated in the treatment of various cancers. … Gemogenovatucel-T is a bi-shRNA furin/Granulocyte Macrophage Colony Stimulating Factor (GMCSF) Augmented autologous tumour cell vaccine.
Nomacopan
go.drugbank.com/drugs/DB14991InvestigationalNomacopan is under investigation in clinical trial NCT03427060 (Coversin in PNH in Patients With Resistance to Eculizumab Due to Complement C5 Polymorphisms).
Isuzinaxib
go.drugbank.com/drugs/DB19109InvestigationalIsuzinaxib is under investigation in clinical trial NCT05758896 (Study of APX-115 in Contrast Induced Acute Kidney Injury in Subjects Undergoing PCI).
Nelutroctiv
go.drugbank.com/drugs/DB21554InvestigationalNelutroctiv is a small molecule drug. Nelutroctiv is under investigation in clinical trial NCT05662215 (A Single and Multiple Ascending Dose Study of CK-3828136 in Healthy Adult Participants).
BRL-101
go.drugbank.com/drugs/DB26477InvestigationalBRL-101 is a biologic drug. BRL-101 is under investigation in clinical trial NCT06300723 (Clinical Study of BRL-101 in Severe SCD).
Enadenotucirev
go.drugbank.com/drugs/DB14873InvestigationalEnadenotucirev is under investigation in clinical trial NCT02636036 (Phase I Study of Enadenotucirev and PD-1 Inhibitor in Subjects With Metastatic or Advanced Epithelial Tumors).
Uteroglobin
go.drugbank.com/drugs/DB14880InvestigationalUteroglobin is under investigation in clinical trial NCT01473264 (Safety, Pk and Anti-inflammatory Effects of CC10 Protein in Premature Infants With Respiratory Distress Syndrome (RDS)).
Retagliptin
go.drugbank.com/drugs/DB14898InvestigationalRetagliptin is under investigation in clinical trial NCT02822534 (The Pharmacokinetics and Pharmacodynamics Study of Single and Multiple Dose of SP2086 in Type 2 Diabetes Patients).
Imidazole-4-carboxylic acid
go.drugbank.com/drugs/DB16194ExperimentalImidazole-4-carboxylic acid is under investigation in clinical trial NCT00583895 (Safety and Efficacy Study of Imcooh Cream in Patients Suffering From Moderate Atopic Dermatitis).
Bepirovirsen
go.drugbank.com/drugs/DB16202InvestigationalIONIS-HBVRx is under investigation in clinical trial NCT04544956 (A Mechanistic Study of GSK3228836 With Fine Needle Aspiration (FNA) in Participants With Chronic Hepatitis B).