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Silibinin
go.drugbank.com/drugs/DB09298InvestigationalSilibinin is the major active constituent of silymarin, a standardized extract of the milk thistle seeds, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silicristin, silidianin
Saposin C
go.drugbank.com/drugs/DB17380InvestigationalBXQ-350 consists of Saposin C and the phospholipid dioleoylphosphatidyl-serine (DOPS), a phospholipid located on cell membranes.
SynOV1.1
go.drugbank.com/drugs/DB17539InvestigationalIt is a recombinant oncolytic adenovirus, controlled by synthetic gene circuit, encoding the human immunostimulating factor cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF).
BBM-H803
go.drugbank.com/drugs/DB17700InvestigationalIt consists of an adeno-associated virus vector containing an expression cassette of the human Factor VIII transgene.
AME-527
go.drugbank.com/drugs/DB05879ExperimentalAME-527 is a humanized monoclonal antibody that recognizes human TNF-alpha (hTNF-alpha) with high affinity and specificity. AME-527 was generated by protein engineering and identified from a library of antibody variants based on its impr...
Spermidine
go.drugbank.com/drugs/DB03566InvestigationalIt is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures. It is a precursor of spermine.
Parsatuzumab
go.drugbank.com/drugs/DB14897InvestigationalParsatuzumab is under investigation in clinical trial NCT01366131 (Study Evaluating the Safety and Efficacy of MEGF0444A in Combination With Carboplatin, Paclitaxel and Bevacizumab in Patients With Advanced
PF-06273340
go.drugbank.com/drugs/DB12269InvestigationalPf 06273340 is under investigation in clinical trial NCT01934738 (A Study to Evaluate Safety, Toleration and Time Course of Plasma Concentration of Multiple Oral Doses of PF-06273340 in Healthy Subjects
RO7300490
go.drugbank.com/drugs/DB17535InvestigationalRO7300490 is under investigation in clinical trial NCT04857138 (A Study to Evaluate Safety, Pharmacokinetics and Anti-tumor Activity of RO7300490, as Single Agent or in Combination With Atezolizumab in
Delocamten
go.drugbank.com/drugs/DB21711InvestigationalDelocamten is under investigation in clinical trial NCT06122779 (Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection