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Displaying results 9041 - 9050 of 10000 in total
  1. Drug

    mRNA-3927

    go.drugbank.com/drugs/DB17669
    Investigational

    mRNA-3927 is an investigational mRNA therapy that consists of two mRNAs that encode for the alpha and beta subunits of the mitochondrial enzyme propionyl-CoA carboxylase (PCC) encapsulated within a lipid … Developed by Moderna Inc., it is being investigated for the treatment of propionic acidemia.[L45998]

  2. Drug

    Tiamulin

    go.drugbank.com/drugs/DB11468
    ExperimentalVet approved

    Tiamulin is a pleuromutilin antibiotic drug that is used in veterinary medicine particularly for pigs and poultry.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP2E1 InhibitorsProducts: PVP-TIAMULIN 10% w/w POWDER, Denagard 80% w/w Coated Premix
  3. Drug

    ZYCOV-D

    go.drugbank.com/drugs/DB15892
    Experimental

    The ZYCOV-D vaccine candidate was developed by Cadila Healthcare Ltd. based in India[A219758]. … Phase I clinical trials of this vaccine candidate were completed in July 2020, with the company reporting successful dosing and tolerance[A219758,L16493].

  4. Drug

    Staurosporine

    go.drugbank.com/drugs/DB02010
    Experimental

    An indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20)

    Categories: P-glycoprotein inhibitors, Heterocyclic Compounds, 2-Ring
  5. Drug

    RGX-111

    go.drugbank.com/drugs/DB17632
    Investigational

    Developed by REGENXBIO Inc., it was investigated for the treatment of mucopolysaccharidosis Type I (MPS I).[L46666] … RGX-111 is an adeno-associated virus vector AAV9 designed to deliver the α-L-iduronidase (IDUA) gene.

    Synonyms: Adeno-associated virus vector serotype 9 expressing human a-L-iduronidase
  6. Drug

    Fenobam

    go.drugbank.com/drugs/DB12931
    Investigational

    Fenobam is under investigation in clinical trial NCT00637221 (Open Label Study Investigating Safety and Efficacy of Fenobam anhydrous 50 mg - 150 mg on Prepulse Inhibition Tests and Continuous Performance … Tasks, Adults With Fragile X Syndrome).

    Categories: Heterocyclic Compounds, 1-Ring
  7. Drug

    Fluindione

    go.drugbank.com/drugs/DB13136
    ApprovedWithdrawn

    Fluindione is under investigation for the treatment of Venous Thrombosis, Pulmonary Embolism, Permanent Atrial Fibrillation, and Anticoagulating Treatment on a Duration at Least 12-month-old Superior.

    Categories: Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index, Vitamin K Antagonists
  8. Drug

    Fluoromisonidazole F-18

    go.drugbank.com/drugs/DB14830
    Investigational

    Fluoromisonidazole F-18 is under investigation in clinical trial NCT01507428 (Study of Positron Emission Tomography and Computed Tomography in Guiding Radiation Therapy in Patients With Stage III Non-small

    Synonyms: 1-(2-Nitro-Imidazolyl)-3-[18F]Fluoro-2-Propanol, 1H-1-(3-[18F]Fluoro-2-Hydroxypropyl-2-Nitroimidazole 18FCategories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Detirelix

    go.drugbank.com/drugs/DB19488
    Experimental

    Detirelix is a small molecule drug. The usage of the INN stem '-relix' in the name indicates that Detirelix is a gonadotropin-releasing-hormone (GnRH) inhibitor. … Detirelix has a monoisotopic molecular weight of 1536.78 Da.

  10. Drug

    Terdecamycin

    go.drugbank.com/drugs/DB19720
    Experimental

    Terdecamycin is a small molecule drug. The usage of the INN stem '-mycin' in the name indicates that Terdecamycin is a antibiotic, produced by Streptomyces strain. … Terdecamycin has a monoisotopic molecular weight of 585.31 Da.