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Displaying results 9041 - 9050 of 10000 in total
  1. Drug

    Ginsenoside Rb1

    go.drugbank.com/drugs/DB06749
    ExperimentalNutraceutical

    Ginsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant genus Panax (ginseng). … Rb1 appears to be most abundant in Panax quinquefolius (American Ginseng). Rb1 seems to affect the reproductive system in animal testicles.

    Synonyms: Arasaponin E1, Panax saponin E
  2. Drug

    Phosphoaminophosphonic acid guanylate ester

    go.drugbank.com/drugs/DB02082
    Experimental

    A non-hydrolyzable analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It binds tightly to G-protein in the presence of Mg2+. … The nucleotide is a potent stimulator of adenylate cyclase.

  3. Drug

    (1R,2S)-2-Phenylcyclopropanaminium

    go.drugbank.com/drugs/DB02665
    Experimental

    A propylamine formed from the cyclization of the side chain of amphetamine. … This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders.

  4. Drug

    Zebularine

    go.drugbank.com/drugs/DB03068
    Experimental

    Also shown to inhibit DNA methylation and tumor growth both in vitro and in vivo. … A chemically stable, cytidine analog that displays anti-tumor properties. It acts as a transition state analog inhibitor of cytidine deaminase by binding to the active site as covalent hydrates.

  5. Drug

    Palmidrol

    go.drugbank.com/drugs/DB14043
    InvestigationalNutraceutical

    A cannabinoid receptor-inactive eCB-related molecule used as prophylactic in helping to prevent respiratory viral infection. … Palmidrol is available for human use as a supplement (400 mg capsules) and as food for medical purposes In Italy and Spain (300 mg and 600 mg tablets).

    Synonyms: Palmitoyl-EA, N-palmitoylethanolamine
  6. Drug

    Zinpentraxin alfa

    go.drugbank.com/drugs/DB14852
    Investigational

    It is under investigation in clinical trial NCT01981850 (A Phase 2 Study Of PRM-151 In Subjects With Myelofibrosis). … Zinpentraxin alfa is a recombinant form of PTX-2, a naturally circulating human protein.

  7. Drug

    Ligufalimab

    go.drugbank.com/drugs/DB17542
    Investigational

    It is under investigation in clinical trial NCT04900350 (A Trial of AK117 (Anti-cd47) in Patients With Myelodysplastic Syndrome). … Ligufalimab is a humanized immunoglobulin G4 (IgG4) monoclonal antibody targeting leukocyte surface antigen CD47.

  8. Drug

    Inarigivir soproxil

    go.drugbank.com/drugs/DB15063
    Investigational

    Inarigivir soproxil is under investigation in clinical trial NCT03434353 (Study to Evaluate the Antiviral Activity of Inarigivir (GS-9992) Plus Tenofovir Alafenamide (TAF) for 12 Weeks in Adults With Chronic

  9. Drug

    Miricorilant

    go.drugbank.com/drugs/DB16234
    Investigational

    Miricorilant is under investigation in clinical trial NCT03818256 (Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Miricorilant (CORT118335) in Obese Adult Patients With Schizophrenia and

  10. Drug

    GDC-0425

    go.drugbank.com/drugs/DB14791
    Investigational

    GDC-0425 is under investigation in clinical trial NCT01359696 (A Study Evaluating the Safety, Tolerability, and Pharmacokinetics of GDC-0425 Administered With and Without Gemcitabine in Patients With Refractory