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QRX-411
go.drugbank.com/drugs/DB17868ExperimentalQRX-411 is a first-in-class RNA-based oligonucleotide designed to restore wild-type USH2A mRNA, leading to the production of the functional USH2A protein. … It addresses the underlying cause of Usher syndrome due to the c.7595-2144A>G mutation in the _USH2A_ gene.[L46777]
Spermidine
go.drugbank.com/drugs/DB03566InvestigationalSpermidine is a polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids. … It is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures. It is a precursor of spermine.
Synonyms: N-(3-Aminopropyl)-1,4-butane-diamine, N-(3-aminopropyl)butane-1,4-diamineChlorophetanol
go.drugbank.com/drugs/DB11368ExperimentalChlorophetanol is an agent known to have antifungal activities.
Ferric oxyhydroxide
go.drugbank.com/drugs/DB14695ExperimentalAn antiferromagnetic material; constitutes the core of natural ferritin.
IK-930
go.drugbank.com/drugs/DB18149InvestigationalIK-930 is an oral, paralog-selective TEAD inhibitor.
RO-5028442
go.drugbank.com/drugs/DB12721InvestigationalRO5028442 has been used in trials studying Autistic Disorder.
ACT-451840
go.drugbank.com/drugs/DB13054InvestigationalACT-451840 has been used in trials studying Malaria.
N,N-dimethylarginine
go.drugbank.com/drugs/DB01686ExperimentalADMA interferes with L-arginine in the production of nitric oxide, a key chemical to endothelial and hence cardiovascular health. … It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells which is closely related to L-arginine, a conditionally-essential amino acid.
Synonyms: N(5)-((Dimethylamino)iminomethyl)-L-ornithine, dimethyl-L-arginineReparixin
go.drugbank.com/drugs/DB12614Investigational1, and Pancreatic Islet Transplantation in Type 1 Diabetes Mellitus. … Reparixin has been used in trials studying the treatment and prevention of Breast Cancer, Metastatic Breast Cancer, Pancreatectomy for Chronic Pancreatitis, Islet Transplantation in Diabetes Mellitus Type
Plamotamab
go.drugbank.com/drugs/DB18944InvestigationalPlamotamab is under investigation in clinical trial NCT05328102 (Phase 2 Study of Plamotamab Combined With Tafasitamab Plus Lenalidomide Versus Tafasitamab Plus Lenalidomide in Relapsed or Refractory (